Miller Kristen, Fischer Max, Kamino Hideko, Meehan Shane, Cohen David
The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, USA.
Dermatol Online J. 2012 Dec 15;18(12):5.
Purpura annularis telangiectoides of Majocchi (PATM) is a clinical variant of pigmented purpuric dermatoses. It is characterized by asymptomatic or mildly pruritic, erythematous, annular patches that vary in size. The patches exhibit central clearing and peripheral cayenne pepper petechiae. It classically occurs on the lower legs but may be more generalized. Histopathologic features include a lymphocytic capillaritis with subsequent capillary leakage and extravasated erythrocytes, which is typical of all pigmented purpuric dermatoses. The pathogenesis of PATM is unknown, but it may uncommonly be associated with underlying diseases such as hematologic disorders and rarely cutaneous T-cell lymphoma. There is no standard effective treatment.
马约基环形毛细血管扩张性紫癜（PATM）是色素性紫癜性皮病的一种临床变体。其特征为无症状或轻度瘙痒的红斑性环形斑块，大小各异。斑块呈现中央消退和周边辣椒粉样瘀点。典型情况下发生于小腿，但也可能更广泛。组织病理学特征包括淋巴细胞性毛细血管炎，随后出现毛细血管渗漏和红细胞外渗，这是所有色素性紫癜性皮病的典型表现。PATM的发病机制尚不清楚，但它可能罕见地与血液系统疾病等基础疾病相关，且极少与皮肤T细胞淋巴瘤有关。目前尚无标准有效的治疗方法。
