姜黄素作为大肠杆菌中淀粉样蛋白的指示剂染料。
Curcumin as an amyloid-indicator dye in E. coli.
机构信息
Department of Chemistry, Stanford University, Stanford, California 94305, USA.
出版信息
Chem Commun (Camb). 2013 May 14;49(39):4193-5. doi: 10.1039/c2cc37792f. Epub 2013 Jan 4.
Abstract
We have demonstrated that curcumin is an amyloid-specific dye in E. coli. Curcumin binds to curliated whole cells and to isolated curli amyloid fibers. Similar to Congo red, curcumin exhibits a red-shift in absorbance and a significant increase in fluorescence upon binding to isolated curli.
摘要
我们已经证明姜黄素是大肠杆菌中一种淀粉样蛋白特异性染料。姜黄素与卷曲菌全细胞和分离的卷曲菌淀粉样纤维结合。与刚果红类似，姜黄素与分离的卷曲菌结合时，其吸收光谱发生红移，荧光显著增强。
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