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[四氧肟酸和二吡肟酸对动物有机磷农药急性中毒的治疗及复活活性的比较研究]

[A comparative study of the therapeutic and reactivating activities of alloxime and dipyroxime in acute poisoning of animals by organophosphate pesticides].

作者信息

Loboda Iu I

出版信息

Farmakol Toksikol. 1990 Jan-Feb;53(1):64-5.

PMID:2328807
Abstract

The therapeutic and reactivating activities of a new antidote alloxime were studied as compared with dipiroxime (TMB-4) during oral intoxication of animals by chlorophos and carbophos (LD50). When administered intramuscularly in a dose of 10 mg/kg, alloxime exhibited more pronounced therapeutic and reactivating effects (particularly in the central nervous system) as compared to dipiroxime.

摘要

在动物经毒死蜱和蝇毒磷口服中毒（半数致死量）期间，将新型解毒剂阿洛肟的治疗和复活活性与双吡啶肟（TMB - 4）进行了比较研究。当以10毫克/千克的剂量肌肉注射时，与双吡啶肟相比，阿洛肟表现出更显著的治疗和复活作用（特别是在中枢神经系统方面）。

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