Maćkowiak J, Sierakowski S, Wiśniewski K
Farmakol Toksikol. 1990 Jan-Feb;53(1):66-7.
Suprofen is a new non-steroidal anti-inflammatory drug administered intragastrically 90 min before roentgen irradiation in a dose of 20 mg/kg and then daily for 10 days in a dose of 10 mg/kg exerts the radioprotective effect evaluated according to a 30-day survival rate and an average life expectancy of the deceased animals as well as according to a decrease of postirradiation leukopenia incidence. A single administration of suprofen following roentgen irradiation exerts no radioprotective effect. Suprofen was found to enhance the radioprotective action of cysteamine.
舒洛芬是一种新型非甾体抗炎药，在进行X射线照射前90分钟以20毫克/千克的剂量胃内给药，然后连续10天每天以10毫克/千克的剂量给药，根据30天存活率、死亡动物的平均预期寿命以及照射后白细胞减少症发病率的降低情况来评估，它具有辐射防护作用。在X射线照射后单次给予舒洛芬则没有辐射防护作用。已发现舒洛芬可增强半胱胺的辐射防护作用。
