• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

巴西阿帕雷西达戈亚尼亚市基层医疗保健诊所中 COPD 的漏诊情况。

Underdiagnosis of COPD at primary health care clinics in the city of Aparecida de Goiânia, Brazil.

机构信息

Serviço de Pneumologia, Hospital das Clínicas, Faculdade de Medicina, Universidade Federal de Goiás, Goiânia, GO, Brasil.

出版信息

J Bras Pneumol. 2012 Nov-Dec;38(6):692-9. doi: 10.1590/s1806-37132012000600003.

DOI:10.1590/s1806-37132012000600003
PMID:23288113
Abstract

OBJECTIVE

To estimate the prevalence of undiagnosed COPD among individuals with risk factors for the disease treated at primary health care clinics (PHCCs) in the city of Aparecida de Goiânia, Brazil.

METHODS

Inclusion criteria were being > 40 years of age, having a > 20 pack-year history of smoking or a > 80 hour-year history of exposure to biomass smoke, and seeking medical attention at one of the selected PHCCs. All subjects included in the study underwent spirometry for the diagnosis of COPD.

RESULTS

We successfully evaluated 200 individuals, mostly males. The mean age was 65.9 ± 10.5 years. The diagnosis of COPD was confirmed in 63 individuals, only 18 of whom had been previously diagnosed with COPD (underdiagnosis rate, 71.4%). There were no significant differences between the subgroups with and without a previous diagnosis of COPD in relation to demographics and risk factors. However, there were significant differences between these subgroups for the presence of expectoration, wheezing, and dyspnea (p = 0.047; p = 0.005; and p = 0.047, respectively). The FEV1 and FEV1/FVC ratio, expressed as percentages of the predicted values, were significantly lower in the subjects with a previous diagnosis of COPD, which was predominantly mild or moderate in both subgroups.

CONCLUSIONS

The rate of underdiagnosis of COPD was high at the PHCCs studied. One third of the patients with risk factors for COPD met the clinical and functional criteria for the disease. It seems that spirometry is underutilized at such facilities.

摘要

目的

评估巴西阿帕雷西达戈亚尼亚市初级保健诊所(PHCC)治疗的患有 COPD 危险因素的个体中未确诊 COPD 的患病率。

方法

纳入标准为年龄>40 岁,吸烟>20 包/年或暴露于生物量烟雾>80 小时/年,以及在选定的 PHCC 之一就诊。所有纳入研究的受试者均接受了肺量计检查以诊断 COPD。

结果

我们成功评估了 200 名个体,主要为男性。平均年龄为 65.9±10.5 岁。63 名患者被确诊为 COPD,其中只有 18 名患者曾被诊断为 COPD(漏诊率为 71.4%)。在有无先前诊断为 COPD 的亚组之间,在人口统计学和危险因素方面无显著差异。然而,在有或无先前诊断为 COPD 的亚组之间,在咳痰、喘息和呼吸困难的存在方面存在显著差异(p=0.047;p=0.005;p=0.047,分别)。FEV1 和 FEV1/FVC 比值,以预测值的百分比表示,在有先前诊断为 COPD 的患者中明显较低,在两个亚组中均主要为轻度或中度。

结论

在研究的 PHCC 中,COPD 的漏诊率较高。三分之一的 COPD 危险因素患者符合该疾病的临床和功能标准。似乎此类设施对肺量计的使用不足。

相似文献

1
Underdiagnosis of COPD at primary health care clinics in the city of Aparecida de Goiânia, Brazil.巴西阿帕雷西达戈亚尼亚市基层医疗保健诊所中 COPD 的漏诊情况。
J Bras Pneumol. 2012 Nov-Dec;38(6):692-9. doi: 10.1590/s1806-37132012000600003.
2
COPD Underdiagnosis and Misdiagnosis in a High-Risk Primary Care Population in Four Latin American Countries. A Key to Enhance Disease Diagnosis: The PUMA Study.四个拉丁美洲国家高危初级保健人群中慢性阻塞性肺疾病的漏诊和误诊。加强疾病诊断的关键:PUMA研究。
PLoS One. 2016 Apr 13;11(4):e0152266. doi: 10.1371/journal.pone.0152266. eCollection 2016.
3
Prevalence, Risk Factors and Diagnostic Accuracy of COPD Among Smokers in Primary Care.基层医疗中吸烟者慢性阻塞性肺疾病的患病率、危险因素及诊断准确性
COPD. 2015 Aug;12(4):404-12. doi: 10.3109/15412555.2014.974736.
4
Detection of COPD in a high-risk population: should the diagnostic work-up include bronchodilator reversibility testing?高危人群中慢性阻塞性肺疾病的检测:诊断检查应包括支气管扩张剂可逆性测试吗?
Int J Chron Obstruct Pulmon Dis. 2015 Feb 23;10:407-14. doi: 10.2147/COPD.S76047. eCollection 2015.
5
Multicenter study of the COPD-6 screening device: feasible for early detection of chronic obstructive pulmonary disease in primary care?慢性阻塞性肺疾病-6筛查设备的多中心研究:在初级保健中早期检测慢性阻塞性肺疾病是否可行?
Int J Chron Obstruct Pulmon Dis. 2017 Aug 4;12:2323-2331. doi: 10.2147/COPD.S136244. eCollection 2017.
6
Prevalence and underdiagnosis of chronic obstructive pulmonary disease among patients at risk in primary care.基层医疗中高危患者慢性阻塞性肺疾病的患病率和漏诊率。
CMAJ. 2010 Apr 20;182(7):673-8. doi: 10.1503/cmaj.091784. Epub 2010 Apr 6.
7
Voluntary lung function screening to reveal new COPD cases in southern Italy.在意大利南部进行自愿肺功能筛查以发现新的慢性阻塞性肺疾病病例。
Int J Chron Obstruct Pulmon Dis. 2017 Jul 11;12:2035-2042. doi: 10.2147/COPD.S136357. eCollection 2017.
8
Determinants of underdiagnosis of COPD in national and international surveys.COPD 漏诊的国内外调查研究。
Chest. 2015 Oct;148(4):971-985. doi: 10.1378/chest.14-2535.
9
Detection of previously undiagnosed cases of COPD in a high-risk population identified in general practice.在全科医学中发现高危人群中以前未诊断的 COPD 病例。
COPD. 2012 Aug;9(5):458-65. doi: 10.3109/15412555.2012.685118. Epub 2012 May 29.
10
[Over-diagnosis of chronic obstructive pulmonary disease in Primary Care. Prevalence and determining factors].[基层医疗中慢性阻塞性肺疾病的过度诊断。患病率及决定因素]
Semergen. 2017 Nov-Dec;43(8):557-564. doi: 10.1016/j.semerg.2016.11.006. Epub 2017 May 17.

引用本文的文献

1
Sociodemographic and clinical characteristics of individuals exposed to smoking or biomass smoke and followed at primary health care centers in Brazil: a multicenter study.在巴西初级卫生保健中心接受随访的接触吸烟或生物质烟雾个体的社会人口学和临床特征:一项多中心研究。
J Bras Pneumol. 2025 Sep 8;51(3):e20250001. doi: 10.36416/1806-3756/e20250001. eCollection 2025.
2
Metabolomic Plasma Profile of Chronic Obstructive Pulmonary Disease Patients.慢性阻塞性肺疾病患者的血浆代谢组学特征
Int J Mol Sci. 2025 May 9;26(10):4526. doi: 10.3390/ijms26104526.
3
Prevalence of chronic respiratory disease using case-finding tools in adults living with noncommunicable disease in low- and middle-income countries: a systematic review.
使用病例发现工具在低收入和中等收入国家患有非传染性疾病的成年人中慢性呼吸道疾病的患病率:一项系统综述
BMC Pulm Med. 2025 May 10;25(1):232. doi: 10.1186/s12890-025-03697-8.
4
Chronic Obstructive Pulmonary Disease Overdiagnosis and Overtreatment: A Meta-Analysis.慢性阻塞性肺疾病的过度诊断与过度治疗:一项荟萃分析
J Clin Med. 2023 Nov 8;12(22):6978. doi: 10.3390/jcm12226978.
5
Undiagnosed and 'overdiagnosed' COPD using postbronchodilator spirometry in primary healthcare settings: a systematic review and meta-analysis.在基层医疗环境中使用支气管扩张剂后肺量测定法诊断和“过度诊断” COPD:系统评价和荟萃分析。
BMJ Open Respir Res. 2023 Apr;10(1). doi: 10.1136/bmjresp-2022-001478.
6
Accuracy and economic evaluation of screening tests for undiagnosed COPD among hypertensive individuals in Brazil.巴西高血压人群中未确诊 COPD 的筛查试验的准确性和经济评估。
NPJ Prim Care Respir Med. 2022 Dec 13;32(1):55. doi: 10.1038/s41533-022-00303-w.
7
Prevalence and incidence of chronic obstructive pulmonary disease in Latin America and the Caribbean: a systematic review and meta-analysis.拉丁美洲和加勒比地区慢性阻塞性肺疾病的患病率和发病率:系统评价和荟萃分析。
BMC Pulm Med. 2022 Jul 16;22(1):273. doi: 10.1186/s12890-022-02067-y.
8
Clinical, laboratory, and functional characteristics of asthma-COPD overlap in patients with a primary diagnosis of COPD.在初诊为 COPD 的患者中,哮喘-COPD 重叠的临床、实验室和功能特征。
J Bras Pneumol. 2020 Nov 6;47(1):e20200033. doi: 10.36416/1806-3756/e20200033. eCollection 2020.
9
Update on the approach to smoking in patients with respiratory diseases.呼吸系统疾病患者吸烟问题处理方法的最新进展。
J Bras Pneumol. 2019 Jun 27;45(3):e20180314. doi: 10.1590/1806-3713/e20180314.
10
Use of the terms "overdiagnosis" and "misdiagnosis" in the COPD literature: a rapid review.慢性阻塞性肺疾病(COPD)文献中“过度诊断”和“误诊”术语的使用:快速综述
Breathe (Sheff). 2019 Mar;15(1):e8-e19. doi: 10.1183/20734735.0354-2018.