Departamento de Epidemiologia Geral e Controle de Doenças, Instituto de Medicina Tropical, Antuérpia, Bélgica.
J Bras Pneumol. 2012 Nov-Dec;38(6):757-60. doi: 10.1590/s1806-37132012000600011.
We evaluated the diagnostic yield of fiberoptic bronchoscopy for the diagnosis of smear-negative pulmonary tuberculosis in patients treated at a referral hospital in Lima, Peru. Of the 611 patients who underwent the procedure, 140 (23%) were diagnosed with tuberculosis based on the analysis of BAL samples. Being young and being male were significantly associated with positive cultures. In addition, 287 patients underwent post-bronchoscopic sputum smear testing for AFB, the results of which increased the diagnostic yield by 22% over that obtained through the analysis of BAL samples alone. We conclude that the analysis of BAL samples and post-bronchoscopic sputum samples provides a high diagnostic yield in smear-negative patients suspected of having pulmonary tuberculosis.
我们评估了在秘鲁利马的一家转诊医院中，对接受治疗的痰涂片阴性肺结核患者进行纤维支气管镜检查的诊断效果。在接受该检查的 611 名患者中，根据 BAL 样本分析，有 140 名（23%）被诊断为肺结核。年轻和男性是与阳性培养物显著相关的因素。此外，287 名患者进行了支气管镜检查后的痰涂片抗酸杆菌检测，这使诊断率比单独分析 BAL 样本提高了 22%。我们得出结论，分析 BAL 样本和支气管镜检查后的痰样本对疑似患有肺结核的痰涂片阴性患者具有较高的诊断效果。
