School of Physiotherapy, University of Otago, Dunedin, New Zealand.
Indian J Pediatr. 2013 Jun;80(6):460-4. doi: 10.1007/s12098-012-0945-z. Epub 2013 Jan 4.
To investigate the effect of Auditory, Tactile, Visual and Vestibular stimulus (ATVV) on neuromotor development in preterm infants.
Fifty preterm infants born at 28-36 wk with a birth weight ranging from 1,000-2,000 g were recruited for the study. They were block randomized into a control group (n = 25) and study group (n = 25). New Ballard score was used for the baseline measurement of neuromaturity in both groups. In neonatal intensive care unit (NICU), the study group received multisensory stimulation for 12 min per session, 5 sessions per wk along with routine NICU care either from 33 wk corrected gestational age for infants born at 28-32 wk or from 48 h of birth for infants born at 33-36 wk until discharge from the hospital. The control group received the routine NICU care. At term age the preterm infants were assessed using Infant Neurological International Battery (INFANIB) and the groups were compared using independent t test.
The multisensory stimulated infants showed higher neuromotor score (p = 0.001) compared to the control group. The french angle components of INFANIB including heel to ear (p = 0.016) and popliteal angle (p = 0.001) were statistically significant between the groups.
Multisensory stimulation appears to have a beneficial effect on the tonal maturation in preterm infants. However, further studies are warranted to investigate the long-term effects of multisensory stimulation on neurodevelopmental outcome in preterm infants.
探讨听觉、触觉、视觉和前庭刺激（ATVV）对早产儿神经运动发育的影响。
本研究纳入了 50 名胎龄 28-36 周、出生体重 1000-2000g 的早产儿。他们被随机分为对照组（n=25）和研究组（n=25）。两组均采用新 Ballard 评分进行神经成熟度的基线测量。在新生儿重症监护病房（NICU）中，研究组在出生后 33 周的校正胎龄（28-32 周出生的婴儿）或出生后 48 小时（33-36 周出生的婴儿）开始，每天接受 12 分钟的多感官刺激，每周 5 次，同时接受常规 NICU 护理，直至出院。对照组接受常规 NICU 护理。在矫正胎龄足月时，采用婴儿神经国际电池（INFANIB）对早产儿进行评估，并采用独立 t 检验比较两组。
多感官刺激组的神经运动评分较高（p=0.001）。INFANIB 的法国角成分，包括足跟到耳朵（p=0.016）和腘窝角（p=0.001），两组间有统计学差异。
多感官刺激似乎对早产儿的音调成熟有有益的影响。然而，需要进一步的研究来探讨多感官刺激对早产儿神经发育结局的长期影响。
