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腹腔镜胃电刺激治疗药物难治性糖尿病和特发性胃轻瘫。

Laparoscopic gastric electrical stimulation for medically refractory diabetic and idiopathic gastroparesis.

机构信息

Cleveland Clinic, Bariatric and Metabolic Institute, Cleveland, OH 44195, USA.

出版信息

J Gastrointest Surg. 2013 Mar;17(3):461-70. doi: 10.1007/s11605-012-2128-7. Epub 2013 Jan 4.

DOI:10.1007/s11605-012-2128-7
PMID:23288718
Abstract

BACKGROUND

Gastric electrical stimulator (GES) implantation is effective in certain patients with gastroparesis; however, laparotomy is often employed for placement. The aim of this study is to review outcomes of patients who underwent laparoscopic GES therapy for diabetic and idiopathic gastroparesis at a large referral center.

METHODS

Patients who underwent GES (Enterra Therapy System; Medtronic, Minneapolis, MN) implantation with subsequent interrogation and programming between March 2001 and November 2011 were analyzed.

RESULTS

A total of 113 patients underwent GES placement or revision during the study period. One hundred eleven patients underwent primary GES at our institution, while two patients underwent GES generator revision at our institution. Primary operations were completed laparoscopically in 110 of 111 cases, with one conversion to laparotomy due to severe adhesions. At a mean follow-up of 27 months (1-113), symptom improvement was achieved in 91 patients (80 %) and was similar for both the diabetic and idiopathic subgroups. Need for supplemental nutrition (enteral and/or parental) decreased in both groups.

CONCLUSIONS

GES placement is feasible using a laparoscopic approach. Medical refractory gastroparesis in the diabetic and idiopathic groups had significant symptom improvement with no difference between the two groups. Need for supplemental nutrition is decreased following GES.

摘要

背景

胃电刺激器(GES)植入术对某些胃轻瘫患者有效;然而,通常采用剖腹手术进行放置。本研究旨在回顾在大型转诊中心接受腹腔镜 GES 治疗的糖尿病和特发性胃轻瘫患者的结局。

方法

分析了 2001 年 3 月至 2011 年 11 月期间接受 GES(Enterra 治疗系统;美敦力,明尼苏达州明尼阿波利斯)植入并随后进行询问和编程的患者。

结果

在研究期间,共有 113 例患者接受了 GES 放置或修正。111 例患者在我们机构接受了原发性 GES,而 2 例患者在我们机构接受了 GES 发生器修正。110 例原发性手术均在腹腔镜下完成,1 例因严重粘连而转为剖腹手术。在平均 27 个月(1-113)的随访中,91 例患者(80%)症状得到改善,糖尿病组和特发性组相似。两组患者的补充营养(肠内和/或肠外)需求均减少。

结论

使用腹腔镜方法可以实现 GES 放置。糖尿病和特发性两组患者的医学难治性胃轻瘫症状均有显著改善,两组之间无差异。GES 后补充营养的需求减少。

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本文引用的文献

1
Hospitalizations and testing in gastroparesis.胃轻瘫的住院治疗和检测。
J Gastroenterol Hepatol. 2011 Aug;26(8):1275-82. doi: 10.1111/j.1440-1746.2011.06735.x.
2
Cellular changes in diabetic and idiopathic gastroparesis.糖尿病性和特发性胃轻瘫的细胞变化。
Gastroenterology. 2011 May;140(5):1575-85.e8. doi: 10.1053/j.gastro.2011.01.046. Epub 2011 Feb 4.
3
Metoclopramide in the treatment of diabetic gastroparesis.甲氧氯普胺治疗糖尿病性胃轻瘫。
通过超声造影评估糖尿病胃轻瘫患者的胃血供情况。
Br J Radiol. 2016 Dec;89(1068):20160366. doi: 10.1259/bjr.20160366. Epub 2016 Oct 19.
4
Gastric Electrical Stimulation for Gastroparesis and Chronic Unexplained Nausea and Vomiting.胃电刺激治疗胃轻瘫及慢性不明原因恶心和呕吐
Curr Treat Options Gastroenterol. 2016 Dec;14(4):386-400. doi: 10.1007/s11938-016-0103-1.
5
Robotic gastric electrical stimulator placement: technique and literature review.机器人胃电刺激器植入:技术与文献综述
J Robot Surg. 2014 Sep;8(3):285-7. doi: 10.1007/s11701-013-0440-1. Epub 2013 Dec 11.
6
Total gastrectomy for rare refractory gastroparesis in patient with syringomyelia: A good impact on quality of life.脊髓空洞症患者罕见难治性胃轻瘫的全胃切除术:对生活质量有良好影响。
Ann Med Surg (Lond). 2015 Oct 30;4(4):444-7. doi: 10.1016/j.amsu.2015.10.016. eCollection 2015 Dec.
7
Gastric Electric Stimulation for Refractory Gastroparesis: A Prospective Analysis of 151 Patients at a Single Center.胃电刺激治疗难治性胃轻瘫:单中心151例患者的前瞻性分析
Dig Dis Sci. 2016 Jan;61(1):168-75. doi: 10.1007/s10620-015-3837-z. Epub 2015 Aug 18.
8
Surgical treatment of medically refractory gastroparesis in the morbidly obese.病态肥胖患者药物难治性胃轻瘫的外科治疗
Surg Endosc. 2015 Sep;29(9):2683-9. doi: 10.1007/s00464-014-3990-z. Epub 2015 Jan 17.
9
Pre-operative opioid analgesia reduces clinical success of laparoscopic gastric electrical stimulation placement in patients with gastroparesis.术前使用阿片类镇痛药会降低胃轻瘫患者腹腔镜胃电刺激置入术的临床成功率。
Surg Endosc. 2015 Apr;29(4):805-9. doi: 10.1007/s00464-014-3754-9. Epub 2014 Aug 13.
10
Treatment of refractory diabetic gastroparesis: Western medicine and traditional Chinese medicine therapies.难治性糖尿病胃轻瘫的治疗:西医与中医治疗方法
World J Gastroenterol. 2014 Jun 7;20(21):6504-14. doi: 10.3748/wjg.v20.i21.6504.
Expert Rev Endocrinol Metab. 2010;5(5):653-662. doi: 10.1586/eem.10.41.
4
Gastric electrical stimulation improves outcomes of patients with gastroparesis for up to 10 years.胃电刺激可改善胃轻瘫患者的治疗效果,最长可达 10 年。
Clin Gastroenterol Hepatol. 2011 Apr;9(4):314-319.e1. doi: 10.1016/j.cgh.2010.12.013. Epub 2010 Dec 23.
5
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Dig Dis Sci. 2011 Apr;56(4):1147-53. doi: 10.1007/s10620-010-1485-x. Epub 2010 Nov 28.
6
Preoperative predictors of significant symptomatic response after 1 year of gastric electrical stimulation for gastroparesis.胃电刺激治疗胃轻瘫 1 年后出现明显症状缓解的术前预测因素。
World J Surg. 2010 Aug;34(8):1853-8. doi: 10.1007/s00268-010-0586-1.
7
Gastroparesis and functional dyspepsia: excerpts from the AGA/ANMS meeting.胃轻瘫和功能性消化不良:AGA/ANMS 会议摘录。
Neurogastroenterol Motil. 2010 Feb;22(2):113-33. doi: 10.1111/j.1365-2982.2009.01434.x. Epub 2009 Dec 9.
8
Association of the status of interstitial cells of Cajal and electrogastrogram parameters, gastric emptying and symptoms in patients with gastroparesis.Cajal 间质细胞状态与胃电参数、胃排空和胃轻瘫患者症状的相关性。
Neurogastroenterol Motil. 2010 Jan;22(1):56-61, e10. doi: 10.1111/j.1365-2982.2009.01365.x. Epub 2009 Jul 13.
9
Gastroparesis and gastroparesis-like syndrome: response to therapy and its predictors.胃轻瘫和类胃轻瘫综合征:治疗反应及其预测因素。
Dig Dis Sci. 2009 May;54(5):1003-10. doi: 10.1007/s10620-009-0717-4. Epub 2009 Mar 10.
10
The incidence, prevalence, and outcomes of patients with gastroparesis in Olmsted County, Minnesota, from 1996 to 2006.1996年至2006年明尼苏达州奥尔姆斯特德县胃轻瘫患者的发病率、患病率及转归情况。
Gastroenterology. 2009 Apr;136(4):1225-33. doi: 10.1053/j.gastro.2008.12.047. Epub 2008 Dec 24.