[接触化学因素的急性非淋巴细胞白血病患者的染色体和有丝分裂异常特征]
[Characteristics of chromosomal and mitotic disorders in patients with acute non-lymphoblastic leukemia exposed to chemical factors].
作者信息
Zedginidze A G, Chakvetadze L V, Abdushelishvili R G, Chinchaladze Ts V, Dzhanashiia M D, Glonti L M
出版信息
Gematol Transfuziol. 1990 Jan;35(1):25-7.
PMID:2328900
Abstract
Cytogenetic and mitotic disorders were studied in 151 patients with acute non-lymphoblastic leukemia. A significant rise in the incidence of clonal disorders with predominant affection of chromosomes 5 and 7, and an increase in the percentage of cases with the presence of pathologic mitoses in hemopoietic cells have been recorded in patients who, due to their occupation, have been exposed to potentially mutagenic chemical substances.
摘要
对151例急性非淋巴细胞白血病患者的细胞遗传学和有丝分裂紊乱进行了研究。在因职业接触潜在诱变化学物质的患者中，已记录到克隆性紊乱的发生率显著上升，主要影响5号和7号染色体，造血细胞中病理性有丝分裂的病例百分比增加。
Zotero 插件