Rakov A A, Shatseva T A, Blinova T S, Rogaleva E Iu, Ponomarenko V M, Rugal' V I
Gematol Transfuziol. 1990 Jan;35(1):27-31.
Cultural, ultrastructural, cytochemical and histological investigations of bone marrow tissue were conducted in 26 patients with varying types of preleukemia states. A number of early structural, morphological and functional signs of hemopoietic disorders of different character and manifestation degree have been revealed. Particularly, a relationship has been established between the pathologic changes appearing in the bone marrow stroma and disorders in the morphological and functional state of the hemopoietic cells.
对26例不同类型白血病前期状态患者的骨髓组织进行了文化、超微结构、细胞化学和组织学研究。揭示了不同性质和表现程度的造血障碍的一些早期结构、形态和功能特征。特别是,已确定骨髓基质中出现的病理变化与造血细胞形态和功能状态的紊乱之间存在关联。