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[非T细胞急性淋巴细胞白血病患儿缓解期骨髓及外周血淋巴细胞亚群特征]

[Characteristics of lymphocyte populations in the bone marrow and peripheral blood of children with non-T cell acute lymphoblastic leukemia during remission].

作者信息

Lenskaia R V, Chernov V M, Adzhimamudova T S, Koliadina E N, Shevdova E Iu, Iurasov S V

出版信息

Gematol Transfuziol. 1990 Jan;35(1):8-10.

PMID:2328904
Abstract

Characteristics of lymphocyte populations in the bone marrow and peripheral blood were comparatively analyzed in children with non-T acute lymphoid leukemia (ALL) during remission, and in the reference group of children with conditionally normal hemopoiesis, as well as with population of lymphocytes obtained from the femur of 22-32-week fetuses. The analysis has shown pronounced changes in the children during remission. The shifts in the structure of lymphocyte population in the bone marrow of children during remission of non-T ALL are considered as compensatory, under conditions of a secondary immunodeficiency due to an abrupt diminution of the absolute number of bone marrow and circulating lymphocytes.

摘要

对非T急性淋巴细胞白血病(ALL)缓解期儿童、条件性造血正常儿童参照组以及从22 - 32周胎儿股骨获取的淋巴细胞群体,比较分析了骨髓和外周血中淋巴细胞群体的特征。分析表明缓解期儿童有明显变化。非T ALL缓解期儿童骨髓中淋巴细胞群体结构的改变被认为是在骨髓和循环淋巴细胞绝对数量突然减少导致继发性免疫缺陷的情况下的一种代偿。

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