Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
Cell Stem Cell. 2013 Jan 3;12(1):8-9. doi: 10.1016/j.stem.2012.12.008.
Thrombopoietin (TPO) attracts much attention as an effective stimulus for blood cell formation in patients with hematopoietic disorders. In this issue of Cell Stem Cell, de Laval et al. (2013) show that TPO can also promote "healthy" hematopoietic stem cells when administered before radiotherapy to minimize HSC injury and mutagenesis in mice.
血小板生成素 (TPO) 作为一种治疗造血系统疾病的有效刺激物，引起了广泛关注。在本期《Cell Stem Cell》中，de Laval 等人（2013 年）表明，TPO 在放疗前给药也可以促进“健康”造血干细胞，从而最大限度地减少小鼠造血干细胞损伤和突变。
