Eskenazi/Wishard Health Services, Indianapolis, Indiana, USA.
J Assoc Nurses AIDS Care. 2013 Jan-Feb;24(1 Suppl):S127-34. doi: 10.1016/j.jana.2012.06.012.
As persons living with HIV infection (PLWH) live longer, primary health care and comorbidity issues have come to the forefront. The diagnosis and treatment of hypertension can affect a number of other comorbid conditions, including metabolic syndrome, lipid abnormalities, cardiovascular disease, and diabetes. Literature specific to hypertension and HIV is limited and most often presented in theory-based, rather than empirically based, articles, with hypertension-specific information presented in small sections of articles on cardiovascular disease. A systematic literature review was conducted to evaluate current research evidence to determine prevalence of hypertension in PLWH and its association with antiretroviral therapy (ART) and HIV-related and traditional risk factors. Evidence surrounding the cause and effect of HIV and ART on hypertension is conflicting and inconclusive; however, the importance of hypertension diagnosis and treatment is clear. Evidence supports use of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of Hypertension Guidelines when treating PLWH.
随着感染艾滋病毒的人(PLWH)寿命的延长,初级卫生保健和合并症问题已成为首要问题。高血压的诊断和治疗会影响许多其他合并症,包括代谢综合征、血脂异常、心血管疾病和糖尿病。针对高血压和 HIV 的文献有限,且大多数是以理论为基础的文章呈现,而关于心血管疾病的文章中只包含一小部分关于高血压的具体信息。我们进行了系统的文献回顾,以评估当前的研究证据,确定 PLWH 中高血压的患病率及其与抗逆转录病毒治疗(ART)以及与 HIV 相关的和传统的风险因素的关系。关于 HIV 和 ART 引起高血压的原因及其影响的证据相互矛盾且尚无定论;然而,诊断和治疗高血压的重要性是明确的。有证据支持在治疗 PLWH 时使用《美国预防、检测、评估与治疗高血压全国联合委员会指南》。