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高血压与 HIV 感染。

Hypertension and HIV infection.

机构信息

Eskenazi/Wishard Health Services, Indianapolis, Indiana, USA.

出版信息

J Assoc Nurses AIDS Care. 2013 Jan-Feb;24(1 Suppl):S127-34. doi: 10.1016/j.jana.2012.06.012.

Abstract

As persons living with HIV infection (PLWH) live longer, primary health care and comorbidity issues have come to the forefront. The diagnosis and treatment of hypertension can affect a number of other comorbid conditions, including metabolic syndrome, lipid abnormalities, cardiovascular disease, and diabetes. Literature specific to hypertension and HIV is limited and most often presented in theory-based, rather than empirically based, articles, with hypertension-specific information presented in small sections of articles on cardiovascular disease. A systematic literature review was conducted to evaluate current research evidence to determine prevalence of hypertension in PLWH and its association with antiretroviral therapy (ART) and HIV-related and traditional risk factors. Evidence surrounding the cause and effect of HIV and ART on hypertension is conflicting and inconclusive; however, the importance of hypertension diagnosis and treatment is clear. Evidence supports use of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of Hypertension Guidelines when treating PLWH.

摘要

随着感染艾滋病毒的人(PLWH)寿命的延长,初级卫生保健和合并症问题已成为首要问题。高血压的诊断和治疗会影响许多其他合并症,包括代谢综合征、血脂异常、心血管疾病和糖尿病。针对高血压和 HIV 的文献有限,且大多数是以理论为基础的文章呈现,而关于心血管疾病的文章中只包含一小部分关于高血压的具体信息。我们进行了系统的文献回顾,以评估当前的研究证据,确定 PLWH 中高血压的患病率及其与抗逆转录病毒治疗(ART)以及与 HIV 相关的和传统的风险因素的关系。关于 HIV 和 ART 引起高血压的原因及其影响的证据相互矛盾且尚无定论;然而,诊断和治疗高血压的重要性是明确的。有证据支持在治疗 PLWH 时使用《美国预防、检测、评估与治疗高血压全国联合委员会指南》。

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