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交叉橄榄耳蜗束的紧张性活动缺失对听力敏感度正常的麻醉豚鼠复合动作电位阈值、幅度及掩蔽现象的影响

Absence of tonic activity of the crossed olivocochlear bundle in determining compound action potential thresholds, amplitudes and masking phenomena in anaesthetised guinea pigs with normal hearing sensitivities.

作者信息

Rajan R, Robertson D, Johnstone B M

机构信息

Department of Physiology, University of Western Australia, Perth, Australia.

出版信息

Hear Res. 1990 Mar;44(2-3):195-207. doi: 10.1016/0378-5955(90)90080-9.

DOI:10.1016/0378-5955(90)90080-9
PMID:2329094
Abstract

In Nembutal- or Urethane-anaesthetised guinea pigs N1 audiograms and N1 input-output functions were measured as were compound action potential (CAP) tuning curves under forward masking and simultaneous masking conditions. Then the crossed olivocochlear bundle was lesioned at the floor of the fourth ventricle and the cochlear responses were re-measured. There were never any changes in the N1 audiograms, input-output functions, or the CAP tuning curves. Thus, the crossed efferent pathways do not appear to play any tonic role in determining cochlear threshold sensitivities, selectivities or masking phenomena in anaesthetised guinea pigs with normal hearing sensitivities.

摘要

在戊巴比妥或氨基甲酸乙酯麻醉的豚鼠中,测量了N1听力图和N1输入-输出函数,以及在正向掩蔽和同时掩蔽条件下的复合动作电位(CAP)调谐曲线。然后,在第四脑室底部损伤交叉橄榄耳蜗束,并重新测量耳蜗反应。N1听力图、输入-输出函数或CAP调谐曲线从未有任何变化。因此,在听力敏感度正常的麻醉豚鼠中,交叉传出通路在决定耳蜗阈值敏感度、选择性或掩蔽现象方面似乎不发挥任何紧张性作用。

相似文献

1
Absence of tonic activity of the crossed olivocochlear bundle in determining compound action potential thresholds, amplitudes and masking phenomena in anaesthetised guinea pigs with normal hearing sensitivities.交叉橄榄耳蜗束的紧张性活动缺失对听力敏感度正常的麻醉豚鼠复合动作电位阈值、幅度及掩蔽现象的影响
Hear Res. 1990 Mar;44(2-3):195-207. doi: 10.1016/0378-5955(90)90080-9.
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Tonic activity of the crossed olivocochlear bundle in guinea pigs with idiopathic losses in auditory sensitivity.特发性听觉敏感性丧失豚鼠的交叉橄榄耳蜗束的紧张性活动
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引用本文的文献

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Cognitive task demands modulate the sensitivity of the human cochlea.认知任务需求会调节人类耳蜗的敏感性。
Front Psychol. 2012 Feb 13;3:30. doi: 10.3389/fpsyg.2012.00030. eCollection 2012.
2
Unexceptional sharpness of frequency tuning in the human cochlea.人类耳蜗中频率调谐的普通敏锐度。
Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18614-9. doi: 10.1073/pnas.0509323102. Epub 2005 Dec 12.