日本一例人兽共患盘尾丝虫病病例。

A human case of zoonotic onchocerciasis in Japan.

作者信息

Hashimoto H, Murakami I, Fujiwara S, Takayasu S, Takaoka H, Uga S, Akao N, Kondo K, Yoshimura H

机构信息

Department of Dermatology, Medical College of Oita, Japan.

出版信息

J Dermatol. 1990 Jan;17(1):52-5. doi: 10.1111/j.1346-8138.1990.tb01609.x.

DOI:10.1111/j.1346-8138.1990.tb01609.x

PMID:2329217

Abstract

A 2-year-old girl living in southwestern Japan had a nodule of 2 months' duration on the left foot. A biopsy from the lesion showed transverse sections of a worm surrounded by granulomatous tissue. The worm was identified as an Onchocerca sp. from the morphological characteristics such as relatively thick cuticles, annular ridges on the cortical layer, and high somatic muscles. Positive serological tests using ELISA for Onchocerca gutturosa and Onchocerca volvulus supported the diagnosis. This was the first case of zoonotic Onchocerca infection detected in Japan. The clinicopathological aspects of zoonotic onchocerciasis of this case were discussed.

摘要

一名居住在日本西南部的2岁女童左脚出现一个持续2个月的结节。对该病变进行活检显示，有一条蠕虫的横切面，周围是肉芽肿组织。根据蠕虫相对较厚的角质层、皮层上的环形嵴以及发达的体肌等形态特征，该蠕虫被鉴定为盘尾丝虫属。使用酶联免疫吸附测定法（ELISA）对牛盘尾丝虫和旋盘尾丝虫进行的血清学检测呈阳性，支持了诊断。这是日本首次检测到的人畜共患盘尾丝虫感染病例。本文讨论了该病例人畜共患盘尾丝虫病的临床病理特征。