Hioki Hirofumi, Kumazaki Setsuo, Izawa Atsushi
Department of Cardiovascular Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto city, Nagano 390-8621, Japan.
J Invasive Cardiol. 2013 Jan;25(1):E11-3.
The development of drug-eluting stents (DES) has dramatically reduced the incidence of in-stent restenosis. Stent fracture (SF) of DESs, however, has recently emerged as a rare but serious complication, which may lead to acute coronary syndrome or sudden cardiac death. DES fracture results from metal fatigue and vessel hemodynamic stress on the stent strut, due to markedly reduced neointimal formation. Although actual incidence of SF is not known, previous reports have demonstrated that SF rates are specific to each DES type. In this report, 2 cases of fracture of a Nobori stent are described, with insights into the mechanisms of SF and strategies for its successful management.
药物洗脱支架（DES）的发展显著降低了支架内再狭窄的发生率。然而，DES的支架断裂（SF）最近已成为一种罕见但严重的并发症，可能导致急性冠状动脉综合征或心源性猝死。由于新生内膜形成明显减少，DES断裂是由金属疲劳和支架支柱上的血管血流动力学应力引起的。虽然SF的实际发生率尚不清楚，但先前的报告表明，SF发生率因每种DES类型而异。在本报告中，描述了2例Nobori支架断裂的病例，并深入探讨了SF的机制及其成功管理策略。
