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[2010年意大利宫颈癌有组织筛查项目的扩展及其过程指标]

[Extension of organised cervical cancer screening programmes in Italy and their process indicators, 2010 activity].

作者信息

Ronco Guglielmo, Giubilato Pamela, Naldoni Carlo, Zorzi Manuel, Anghinoni Emanuela, Scalisi Aurora, Dalla Palma Paolo, Zanier Loris, Barca Alessandra, Angeloni Claudio, Gaimo Maria Donata, Maglietta Rocco, Mancini Ettore, Pizzuti Renato, Iossa Anna, Segnan Nereo, Zappa Marco

机构信息

CPO Piemonte, Torino.

出版信息

Epidemiol Prev. 2012 Nov-Dec;36(6 Suppl 1):39-54.

PMID:23293270
Abstract

Italian national guidelines recommend to regions the implementation of organised screening programmes for cervical cancer. As in previous years since 1998 we collected aggregated tables of data from Italian organised cervical screening programmes in order to centrally compute process indicators. Data on women invited during 2010 and screened up to April 2011 were considered. In 2010, the target population of Italian organised screening programmes included 13,538,080 women, corresponding to 80.1% of Italian women aged 25-64 years. Compliance to invitation was 39.8%, with a strong North-South decreasing trend. However, it should be considered that many women are screened outside organised programmes. Among screened women, 4.7% were referred for repeat cytology and 62.7% of them complied; 2.5% of screened women were referred to colposcopy. Compliance with colposcopy referral was 85.9% among women referred because of ASC-US or more severe cytology and 88.7% among those referred because of HSIL or more severe cytology. The positive predictive value (PPV) of referral because of ASC-US or more severe cytology for CIN2 or more severe histology was 16.0%. The unadjusted detection rate of CIN2 or more severe histology was 3.2 per 1,000 screened women (3.5 standardised on the Italian population, truncated 25-64).

摘要

意大利国家指南建议各地区实施宫颈癌有组织的筛查项目。自1998年以来,与前几年一样,我们收集了意大利有组织的宫颈癌筛查项目的数据汇总表,以便集中计算过程指标。考虑了2010年受邀并在2011年4月前接受筛查的女性的数据。2010年,意大利有组织的筛查项目的目标人群包括13538080名女性,占25 - 64岁意大利女性的80.1%。邀请的依从率为39.8%,呈现出明显的从北到南递减趋势。然而,应该考虑到许多女性是在有组织的项目之外接受筛查的。在接受筛查的女性中,4.7%被转诊进行重复细胞学检查,其中62.7%的人依从;2.5%的接受筛查的女性被转诊至阴道镜检查。因非典型鳞状细胞不能明确意义(ASC-US)或更严重细胞学结果而被转诊的女性中,阴道镜检查的依从率为85.9%;因高度鳞状上皮内病变(HSIL)或更严重细胞学结果而被转诊的女性中,依从率为88.7%。因ASC-US或更严重细胞学结果而转诊至CIN2或更严重组织学结果的阳性预测值(PPV)为16.0%。CIN2或更严重组织学结果的未调整检出率为每1000名接受筛查的女性中有3.2例(根据意大利人群标准化后为3.5例,年龄范围截断为25 - 64岁)。

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