Technische Universität Dortmund, Otto-Hahn-Strasse 6, 44227 Dortmund, Germany.
Chem Commun (Camb). 2013 May 14;49(39):4337-9. doi: 10.1039/c2cc37154e. Epub 2013 Jan 7.
Herein preparative scale access to the shared precursor of the fusicoccane family of diterpenoids through biosynthesis in three different microbial hosts is reported. A method to purify the metabolite in high purity and on a preparative scale was explored.
本文报道了通过在三种不同微生物宿主中的生物合成,在制备规模上获得 fusicoccane 二萜类化合物家族的共享前体。还探索了一种在制备规模上高纯度纯化代谢物的方法。