Shimamoto T, Ohyashiki J, Utsumi K, Ohyashiki K, Toyama K
First Department of Internal Medicine, Tokyo Medical College.
Rinsho Ketsueki. 1990 Feb;31(2):249-53.
We report here a patient who was diagnosed as having acute lymphoblastic leukemia (ALL-L2) and colon carcinoma simultaneously and a successful operation for the colon carcinoma was performed preceded to the treatment of ALL. The patient was a 43-year-old male who presented with acute abdominal symptoms and was diagnosed as ALL by the hematological examination and as colon carcinoma (well differentiated adenocarcinoma, Borrmann II) by colon fiberscope. The patient was underwent sigmoidcolectomy for colon carcinoma and was received antibiotics as well as recombinant human granulocyte colony-stimulating factor (rhG-CSF), Approximately two weeks later, the patient received AdVP (Adriamycin, vincristine, and prednisolone) for ALL and achieved a complete remission. It might be possible for some leukemia patients manifesting acute abdominal symptoms to perform surgical approaches, since the prognosis of leukemia patients improved and supportive therapies, including an application of rh-CSF, have developed.
我们在此报告一名同时被诊断为急性淋巴细胞白血病（ALL-L2）和结肠癌的患者，在进行ALL治疗之前成功进行了结肠癌手术。该患者为43岁男性，出现急性腹部症状，经血液学检查诊断为ALL，经结肠纤维镜检查诊断为结肠癌（高分化腺癌，Borrmann II型）。该患者接受了结肠癌乙状结肠切除术，并接受了抗生素以及重组人粒细胞集落刺激因子（rhG-CSF）治疗。大约两周后，该患者接受了ALL的AdVP（阿霉素、长春新碱和泼尼松龙）治疗并实现了完全缓解。由于白血病患者的预后有所改善且包括应用rh-CSF在内的支持疗法得到了发展，对于一些表现出急性腹部症状的白血病患者而言，采取手术治疗或许是可行的。
