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代谢综合征患者的精神障碍。中心性肥胖的关键作用。

Mental disorders in patients with metabolic syndrome. The key role of central obesity.

机构信息

Department of Public Health, Clinical and Molecular Medicine-Section of Psychiatry and Psychiatric Clinic, University of Cagliari, Cagliari, Italy.

出版信息

Eat Weight Disord. 2012 Dec;17(4):e259-66. doi: 10.3275/8809. Epub 2013 Jan 8.

Abstract

BACKGROUND

The Authors sought to evaluate current prevalence of mental disorders in patients affected by metabolic syndrome compared with patients affected by central obesity alone.

METHODS

186 (63.5%) patients affected by central obesity and 107 (36.5%) affected by metabolic syndrome according to ICF criteria were interviewed by means of SCID I.

RESULTS

Axis I current prevalence was respectively 45.7% and 44.9% among patients with central obesity and patients with metabolic syndrome, differences which were not significant. No statistically significant differences were found between groups as far as each single axis I diagnostic category was concerned. Moreover, current prevalence of any axis I, anxiety and mood disorders were independent of the number of components of metabolic syndrome.

CONCLUSION

metabolic syndrome is associated to an higher risk for current mental disorders, which seems to be mainly due to the strong association of central obesity to psychopathology.

摘要

背景

作者旨在评估患有代谢综合征的患者与仅患有中心性肥胖的患者相比,当前精神障碍的患病率。

方法

通过 SCID I 对 186 名(63.5%)患有中心性肥胖的患者和 107 名(36.5%)患有代谢综合征的患者进行访谈。

结果

患有中心性肥胖的患者和患有代谢综合征的患者中,当前轴 I 患病率分别为 45.7%和 44.9%,差异无统计学意义。在各个单一的轴 I 诊断类别方面,两组之间未发现统计学上的显著差异。此外,任何轴 I、焦虑和心境障碍的当前患病率均与代谢综合征的组成部分数量无关。

结论

代谢综合征与当前精神障碍的风险增加有关,这似乎主要归因于中心性肥胖与精神病理学的强烈关联。

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