Nephrology and Dialysis Center, Department of Medicine, Renal Division, Coney Island Hospital, Brooklyn, NY, USA.
Am J Ther. 2013 Jan;20(1):107-10. doi: 10.1097/MJT.0b013e3182541ca2.
The first case of man who presented to psychiatry emergency room for evaluation of abnormal behavior because of urinary stones was reported. Careful evaluation of patient led to a diagnosis of 37 urinary bladder stones in an Egyptian man with obstructive uropathy and metabolic defects in the form of hyperoxaluria and hypocitraturia. Knowledge of the differential diagnosis of metabolic defects can lead to successful outcome in preventing reformation of urinary tract stones after surgery. A 61-year-old Egyptian man presented to psychiatry emergency room because he was found lying on floor in bathroom to urinate by his wife who thought her husband needed psychiatric evaluation. Patient gave history of frequent urination and dysuria on and off for 3 years. In the last 3 months before his presentation to emergency room, he got into a habit of lying down on his left side when he went to bathroom to urinate because it was easier for him to pass urine. Renal consultation requested because of presence of red blood cells in urinalysis. Computed tomography of the abdomen and pelvis showed bilateral hydronephrosis and multiple bladder stones. Twenty-four-hour urine collection showed low urinary citrate and high oxalate. Patient underwent open vesicolithotomy and removal of 36 stones. Stone analysis showed 75% uric acid and 25% calcium oxalate. Patient did very well after surgery, and 1 month later, he underwent transuretheral resection of prostate without any complications. Now patient has no difficulty passing urine and he has no recent attack of urinary tract infection. Knowledge of the differential diagnosis of metabolic defects in men with urinary bladder stones would hopefully provide clinicians with the proper diagnostic tools to more specifically treat such patients with improved success in preventing reformation of urinary tract stones after surgery.
首例因尿路结石所致异常行为而就诊于精神科急诊的患者被报道。对患者的仔细评估导致诊断为埃及男性患者的 37 个膀胱结石,伴有尿路梗阻和代谢缺陷,表现为高草酸尿症和低柠檬酸尿症。了解代谢缺陷的鉴别诊断可以在预防手术后尿路结石再形成方面取得成功。一名 61 岁的埃及男性因被妻子发现躺在浴室地板上小便而被送到精神科急诊,妻子认为丈夫需要进行精神评估。患者有尿频和尿痛病史,时有时无,已持续 3 年。在他到急诊就诊前的 3 个月,他养成了左侧卧位小便的习惯,因为这样更容易排尿。由于尿分析中存在红细胞,因此请求肾科会诊。腹部和骨盆的计算机断层扫描显示双侧肾积水和多个膀胱结石。24 小时尿液收集显示低尿柠檬酸和高草酸盐。患者接受了开放性膀胱结石切除术并取出 36 颗结石。结石分析显示 75%为尿酸,25%为草酸钙。患者术后恢复良好,1 个月后接受经尿道前列腺切除术,无任何并发症。现在患者排尿无困难,最近也没有尿路感染发作。了解男性膀胱结石代谢缺陷的鉴别诊断有望为临床医生提供适当的诊断工具,更具体地治疗此类患者,提高预防手术后尿路结石再形成的成功率。