Auger R G, McManis P G
Department of Neurology, Mayo Clinic, Rochester, MN 55905.
Neurology. 1990 May;40(5):759-63. doi: 10.1212/wnl.40.5.759.
We describe 4 patients with severe trigeminal sensory neuropathy whose main disability resulted from impaired intraoral sensation associated with disturbances of mastication and swallowing. Each patient had an abnormal blink reflex and jaw jerk. In addition, the masseter inhibitory reflex was absent in 3 patients and abnormal in the 4th. This reflex plays a role in the reflex control of mastication and can easily be elicited in normal subjects by stimulation of the skin and mucous membrane in the distribution of the 2nd and 3rd divisions of the trigeminal nerve while the jaw-closing muscles are contracting. Disturbed intraoral sensation combined with impaired trigeminal reflexes (particularly the masseter inhibitory reflex) interferes with neural mechanisms that regulate chewing and can be a source of severe disability in patients with trigeminal sensory neuropathy.
我们描述了4例严重三叉神经感觉神经病变患者，其主要残疾是由与咀嚼和吞咽障碍相关的口腔内感觉受损所致。每位患者均有异常的眨眼反射和下颌反射。此外，3例患者咬肌抑制反射消失，第4例异常。该反射在咀嚼的反射控制中起作用，在正常受试者中，当闭口肌收缩时，通过刺激三叉神经第二和第三分支分布区域的皮肤和黏膜很容易引出。口腔内感觉紊乱与三叉神经反射受损（尤其是咬肌抑制反射）相结合，会干扰调节咀嚼的神经机制，并且可能是三叉神经感觉神经病变患者严重残疾的一个原因。
