State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.
Chin J Nat Med. 2012 Jan;10(1):24-7. doi: 10.1016/S1875-5364(12)60005-3.
To study the chemical constituents of the whole plant of Chloranthus japonicus.
Compounds were isolated and purified by column chromatography. Their structures were elucidated on the basis of spectroscopic methods.
Six sesquiterpenoids were obtained and their structures were identified as chlojaponilactone A (1), atractylenolide III (2), neolitacumone B (3), 10α-hydroxy-1-oxoeremophila-7(11), 8(9)-diene-8, 12-olide (4), shizukanolide C (5), and shizukanolide H (6).
Compound 1 is a new eudesmane-type sesquiterpenoid lactone, and compounds 3 and 4 have been isolated from this species for the first time.
研究金粟兰全株的化学成分。
采用柱色谱法对化合物进行分离纯化，根据光谱数据鉴定其结构。
分离得到 6 个倍半萜类化合物，鉴定为：金粟兰内酯 A（1）、苍术内酯 III（2）、新北美芹素酮 B（3）、10α-羟基-1-氧-埃罗美菲烷-7(11)，8(9)-二烯-8，12-内酯（4）、重楼呋喃 C（5）和重楼呋喃 H（6）。
化合物 1 为新的愈创木烷型倍半萜内酯，化合物 3 和 4 为该种首次分离得到的化合物。
