Vinci G G, Fasullo S
Riv Neurol. 1979 Jul-Aug;49(4):310-22.
A case of acromegaly with peripheral neuropathy characterized by acroparaesthesiae in the median nerve field of both sides is presented. Electrophysiological examination shows bilateral slowing of the motor conduction velocity of the median nerve through the carpal tunnel. The possible pathogenetic mechanisms of the peripheral neuropathy in acromegalic are discussed in the light of the most recent theories about the GH action. Suggestions are made that some associated hormonal disorders diabetes, hyperaldosteronism, hyperthyroidism) can play some part in the neuropathy pathogenesis.
本文报告1例肢端肥大症合并周围神经病变，其特征为双侧正中神经分布区感觉异常。电生理检查显示双侧正中神经经腕管处运动传导速度减慢。结合最新的生长激素作用理论，探讨了肢端肥大症患者周围神经病变可能的发病机制。提出一些相关的激素紊乱（糖尿病、醛固酮增多症、甲状腺功能亢进症）可能在神经病变的发病机制中起一定作用。
