Kageyama J, Satoh K, Kawase Y, Kojima K, Tamai T, Ohkawa M, Tanabe M, Shirakawa Y, Oguri K
Department of Radiology, Kagawa Medical School.
Kokyu To Junkan. 1990 Mar;38(3):273-6.
It is well known that paraquat causes severe organ-toxicity and pulmonary damage. We observed the progress of a patient who survived paraquat poisoning, and we recorded the changes in the lung by high resolution CT. The patient was a 35-year-old man who attempted suicide by paraquat (Guramoxone 100 ml) ingestion. At the time of hospitalization, there was no respiratory involvement. Five days after ingestion, an X-ray examination showed only indistinct vascularity of both lung fields, but high resolution CT showed increased density in the central part of both lung fields. According to the clinical progress after ingestion, mediastinal and subcutaneous emphysema were noted by chest X-ray examination. On the other hand, severe interstitial pneumonia progression of severe lung fibrosis with a decrease in lung volume and interstitial pulmonary emphysema in addition to mediastinal, subcutaneous emphysema were seen by high resolution CT. High resolution CT is useful for detecting morphologic change and diagnosing clinical stages. Observing the course of changes by high resolution CT is useful for deciding the course of clinical therapy, and we have no hesitation in affirming that it should be used in such cases.
众所周知，百草枯会导致严重的器官毒性和肺部损伤。我们观察了一名百草枯中毒幸存者的病情进展，并通过高分辨率CT记录了肺部的变化。该患者为一名35岁男性，吞食了100毫升百草枯（克无踪）企图自杀。住院时，无呼吸受累情况。吞食后5天，X线检查仅显示双肺野血管影模糊，但高分辨率CT显示双肺野中央部分密度增加。根据吞食后的临床进展，胸部X线检查发现纵隔和皮下气肿。另一方面，高分辨率CT显示除纵隔、皮下气肿外，还出现严重的间质性肺炎、严重肺纤维化进展伴肺容积减小和间质性肺气肿。高分辨率CT有助于检测形态学变化和诊断临床分期。通过高分辨率CT观察变化过程有助于决定临床治疗方案，我们毫不犹豫地肯定在这种情况下应使用它。
