Knudsen L B, Helweg-Larsen K
Sundhedsstyrelsen, København.
Ugeskr Laeger. 1990 Apr 16;152(16):1164-7.
Differences in the incidence of infant mortality due to sudden infant death syndrome between the regions of the three Institutes of Forensic Medicine in Denmark are known to exist. To investigate whether these could be due to differences in incidence of causes of death such as suffocation and respiratory infections, the rates and types of autopsy were analysed regarding these death causes. The number of deaths due to these causes and the development in the incidence cannot explain the variation of the incidence of SIDS, in the areas observed. For each of the three periods under consideration (1972-1975, 1976-1979, 1980-1983) the variation between institutes in SIDS-rate is relatively larger than the variation in the total rate of deaths due to these three groups of death causes. In the latest period the total rate is 1.93, 1.77 and 1.27 per 1,000 liveborn in Cophenhagen, Odense and Arhus areas, respectively. The study suggests different evaluations of the results of autopsy. A higher incidence of deaths due to congenital heart defects is seen in Arhus, where the lowest incidence of SIDS is observed. A prospective study (1987-1988) of all cases of sudden infant death in Denmark was initiated by the three forensic Institutes with the aim of evaluating possible time and regional incidence variations using identical diagnostic criteria.
丹麦三所法医学研究所所在地区因婴儿猝死综合征导致的婴儿死亡率差异是已知存在的。为了调查这些差异是否可能归因于诸如窒息和呼吸道感染等死因发生率的不同,对这些死因的尸检率和类型进行了分析。这些死因导致的死亡数量以及发生率的变化并不能解释所观察地区婴儿猝死综合征发生率的差异。在所考虑的三个时期(1972 - 1975年、1976 - 1979年、1980 - 1983年)中,各研究所之间婴儿猝死综合征发生率的差异相对大于这三组死因导致的总死亡率的差异。在最近一个时期,哥本哈根、欧登塞和奥胡斯地区每1000例活产儿中的总死亡率分别为1.93、1.77和1.27。该研究表明对尸检结果存在不同的评估。在奥胡斯地区,先天性心脏缺陷导致的死亡发生率较高,而该地区的婴儿猝死综合征发生率最低。丹麦的三所法医学研究所发起了一项对丹麦所有婴儿猝死病例的前瞻性研究(1987 - 1988年),目的是使用相同的诊断标准评估可能的时间和地区发生率差异。