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胃袖状切除术行幽门窦大部切除术对胃排空的影响

Radical resection of the pyloric antrum and its effect on gastric emptying after sleeve gastrectomy.

机构信息

First Surgical Department, General Faculty Hospital and First Faculty of Medicine, Charles University, U nemocnice 2, 128 08, Prague 2, Czech Republic.

出版信息

Obes Surg. 2013 Apr;23(4):567-73. doi: 10.1007/s11695-012-0850-6.

Abstract

BACKGROUND

The surgical technique of laparoscopic sleeve gastrectomy (LSG) has not been fully standardized yet and there is the unresolved question of what is the optimum size of retained pyloric antrum. The aim of our research was to prove that even after a radical resection of the pyloric antrum the physiological stomach evacuation function can still be preserved.

METHODS

Our study was based on 12 patients, who were randomly divided into two groups. Patients undergoing radical antrum resection (RA group) underwent gastric emptying scintigraphy to determine the evacuation half-time (T1/2) and food retention in the 90th minute of the test (%GE) both before the operation and 3 months afterward. Patients in whom the antrum was preserved (PA group) served as a control group for comparison of postoperative weight loss (in kilogram), decrease in body mass index (BMI), and decline in excess weight (%EWL). The resulting changes were statistically processed.

RESULTS

In the RA group, the average time T1/2 declined from 57.5 to 32.25 min (p = 0.016) and average retention %GE dropped from 20.5 to 9.5% (p = 0.073). Differences in the average values of weight, BMI, or %EWL between both groups were of no statistical significance (p > 0.8).

CONCLUSIONS

In the RA group, an increase in gastric emptying postoperatively was noted. Complications such as failure of stomach evacuation were not observed in the RA group. Our results suggest that even more radical resection of the pyloric antrum performed by LSG is possible without concerns of postoperative disorder of the stomach evacuation function.

摘要

背景

腹腔镜袖状胃切除术(LSG)的手术技术尚未完全标准化,仍然存在一个悬而未决的问题,即保留的幽门窦的最佳大小是多少。我们的研究目的是证明即使进行了幽门窦的根治性切除术,胃的生理排空功能仍能保留。

方法

我们的研究基于 12 名患者,他们被随机分为两组。行根治性窦切除术(RA 组)的患者进行胃排空闪烁显像术,以确定手术前后 3 个月的排空半衰期(T1/2)和测试第 90 分钟时的食物残留(%GE)。保留窦部的患者(PA 组)作为对照组,比较术后体重减轻(以千克为单位)、体重指数(BMI)下降和多余体重百分比(%EWL)下降。对所得变化进行了统计学处理。

结果

在 RA 组,平均 T1/2 从 57.5 分钟降至 32.25 分钟(p = 0.016),平均 %GE 从 20.5%降至 9.5%(p = 0.073)。两组间的平均体重、BMI 或 %EWL 差异无统计学意义(p > 0.8)。

结论

在 RA 组,术后胃排空增加。在 RA 组未观察到胃排空失败等并发症。我们的结果表明,LSG 行更激进的幽门窦切除术,不会导致术后胃排空功能紊乱。

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