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[血浆置换治疗肾移植后血管性排斥反应的经验]

[Experiences with plasmapheresis in the treatment of vascular rejection following kidney transplantation].

作者信息

Eismann R, Konert J, Langkopf B

机构信息

Urologische Universitätsklinik und Poliklinik, Martin-Luther-Universität Halle-Wittenberg.

出版信息

Z Urol Nephrol. 1990 Jan;83(1):9-12.

PMID:2330764
Abstract

In the first 6 weeks after kidney transplantation 15 patients suffering from vascular rejection were treated by 46 plasmapheres. In transplants with additional interstitial rejection the plasmapheresis was introduced after failure of ATG therapy. In 1 patient no histological confirmation was done. In 4 patients the plasmapheresis was successful and in 6 patients suffering from combined vascular and interstitial rejection the ATG therapy was successful only after initial plasmapheresis. In 4 cases the therapy failed to reverse rejection. The early use of plasmapheresis is recommended to obtain the best results.

摘要

在肾移植后的前6周,对15例发生血管排斥反应的患者进行了46次血浆置换治疗。对于伴有间质排斥反应的移植患者,在抗胸腺细胞球蛋白(ATG)治疗失败后采用血浆置换。有1例患者未进行组织学确诊。4例患者血浆置换治疗成功,6例同时发生血管和间质排斥反应的患者,在最初进行血浆置换后,ATG治疗才取得成功。4例患者的治疗未能逆转排斥反应。建议早期使用血浆置换以获得最佳效果。

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1
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Z Urol Nephrol. 1990 Jan;83(1):9-12.
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