State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, P R China.
J Sep Sci. 2013 Feb;36(3):602-8. doi: 10.1002/jssc.201200693. Epub 2013 Jan 10.
A series of cis- and trans-isomers of hydrazone derivatives were separated and analyzed through HPLC with diode-array detection and HPLC-MS/MS using ESI and ion trap MS. Two single crystals (A-5-1 and C-2-1) of the trans-isomers were obtained and determined using X-ray crystallography data, and the cis- to trans-isomerization under different conditions was discussed. Both of the cis- and trans-isomers of A-4 and A-5 exhibited good insecticidal activities against Plutella xylostella.
通过 HPLC 与二极管阵列检测以及 HPLC-MS/MS 联用 ESI 和离子阱 MS，分离和分析了一系列腙衍生物的顺式和反式异构体。得到了反式异构体的两个单晶（A-5-1 和 C-2-1），并通过 X 射线晶体学数据进行了确定，并讨论了在不同条件下顺式到反式的异构化。A-4 和 A-5 的顺式和反式异构体均对小菜蛾表现出良好的杀虫活性。
