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Regulation of AID, the B-cell genome mutator.
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Negative regulation of activation-induced cytidine deaminase in B cells.
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Activation-induced deaminase: light and dark sides.
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Complex regulation and function of activation-induced cytidine deaminase.
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RNA Exosome and Non-coding RNA-Coupled Mechanisms in AID-Mediated Genomic Alterations.
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Transcription elongation factor ELOF1 is required for efficient somatic hypermutation and class switch recombination.
Mol Cell. 2025 Apr 3;85(7):1296-1310.e7. doi: 10.1016/j.molcel.2025.02.007. Epub 2025 Mar 5.
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APOBEC Mutagenesis in Cancer Development and Susceptibility.
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DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification.
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APE2: catalytic function and synthetic lethality draw attention as a cancer therapy target.
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A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus.
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3
Close proximity to Igh is a contributing factor to AID-mediated translocations.
Mol Cell. 2012 Sep 28;47(6):873-85. doi: 10.1016/j.molcel.2012.06.036. Epub 2012 Aug 2.
4
The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation.
J Biol Chem. 2012 Sep 21;287(39):32415-29. doi: 10.1074/jbc.M112.351569. Epub 2012 Jul 26.
5
Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications.
Semin Immunol. 2012 Aug;24(4):264-72. doi: 10.1016/j.smim.2012.05.006. Epub 2012 Jul 6.
7
Immunoglobulin class-switch DNA recombination: induction, targeting and beyond.
Nat Rev Immunol. 2012 Jun 25;12(7):517-31. doi: 10.1038/nri3216.
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Activation induced deaminase: how much and where?
Semin Immunol. 2012 Aug;24(4):246-54. doi: 10.1016/j.smim.2012.05.001. Epub 2012 Jun 9.
9
Spatial organization of the mouse genome and its role in recurrent chromosomal translocations.
Cell. 2012 Mar 2;148(5):908-21. doi: 10.1016/j.cell.2012.02.002. Epub 2012 Feb 16.
10
DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes.
Nature. 2012 Feb 7;484(7392):69-74. doi: 10.1038/nature10909.

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