Azorin J M, Pupeschi G, Valli M, Joanny P, Raucoules D, Lancon C, Tissot R
Department of Psychiatry, Timone Hospital, Marseille, France.
Acta Psychiatr Scand. 1990 Jan;81(1):14-8. doi: 10.1111/j.1600-0447.1990.tb06442.x.
Plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) were found to be significantly higher in manic patients than in age- and sex-matched normal controls (n = 22). In 18 manic patients plasma MHPG correlated with manic symptoms but not with anxiety, depression, motor behaviour, acute psychosis, schizophrenia and severity of illness. A positive correlation between MHPG and grandiosity items on rating scales suggests a link with cognitive contents and therefore a relationship with central factors.
研究发现，躁狂症患者血浆中3-甲氧基-4-羟基苯乙二醇（MHPG）的水平显著高于年龄和性别匹配的正常对照组（n = 22）。在18名躁狂症患者中，血浆MHPG与躁狂症状相关，但与焦虑、抑郁、运动行为、急性精神病、精神分裂症及疾病严重程度无关。评分量表上MHPG与夸大项目之间的正相关表明其与认知内容存在联系，因此与中枢因素有关。
