Division of Nephrology, Department of Medicine, Duke University and Durham VA Medical Centers, Durham, NC 27710, USA.
Cell Metab. 2013 Jan 8;17(1):1-2. doi: 10.1016/j.cmet.2012.12.009.
The epidemiological association between high salt intake and hypertension is well established. However, in most patients, the specific defect causing salt-dependent hypertension cannot be discerned. In this issue of Cell Metabolism, Rakova and associates use an unprecedented study design to characterize long-term salt balance in humans (Rakova et al., 2012).
高盐摄入与高血压之间的流行病学关联已得到充分证实。然而,在大多数患者中,导致盐依赖性高血压的具体缺陷仍难以确定。在本期《细胞代谢》中,Rakova 及其同事采用了一项前所未有的研究设计来描述人类的长期盐平衡状况(Rakova 等人,2012 年)。