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日本三胞胎妊娠的临床特征和短期结局。

Clinical features and short-term outcomes of triplet pregnancies in Japan.

机构信息

Center for Perinatal Medicine, Hokkaido University Hospital, Sapporo, Japan.

出版信息

Int J Gynaecol Obstet. 2013 Apr;121(1):86-90. doi: 10.1016/j.ijgo.2012.10.022. Epub 2013 Jan 8.

Abstract

OBJECTIVE

To review clinical features and short-term outcomes of triplet pregnancies among Japanese women.

METHODS

A retrospective analysis was carried out among 320 Japanese women with triplet pregnancies (8 monochorionic, 75 dichorionic, and 150 trichorionic triplets; 87 with unknown placental chorionicity) who delivered at 22 gestational weeks or more between January 2005 and December 2008.

RESULTS

Delivery was by cesarean for 315 (98%) women. Gestational age at delivery was 32.3±2.8 weeks (mean±SD) and 33.2 weeks (median), and 97%, 61%, and 14% of women delivered at less than 37, less than 34, and less than 30 gestational weeks, respectively. For live-born infants, mean birth weight was 1762±437 g, 1608±396 g, and 1406±380 g for the heaviest, middle, and lightest triplet, respectively. Eighteen (5.6%) women experienced perinatal mortality (3 triplets for 1 woman, 2 triplets for 4 women, and 1 triplet for 13 women). Perinatal mortality was 25 deaths per 1000 deliveries, and decreased with increasing number of chorionic membranes (125, 44, and 20 per 1000 mono-, di-, and trichorionic triplet deliveries, respectively).

CONCLUSION

Short-term outcomes were good among triplet pregnancies in Japan. The data may be useful for counseling Japanese women with triplet pregnancies.

摘要

目的

回顾日本女性三胞胎妊娠的临床特征和短期结局。

方法

对 2005 年 1 月至 2008 年 12 月期间分娩的 320 名 22 孕周及以上的三胞胎妊娠妇女(8 例单绒毛膜,75 例双绒毛膜,150 例三绒毛膜;87 例胎盘绒毛膜性未知)进行回顾性分析。

结果

315 名(98%)妇女行剖宫产分娩。分娩时的孕龄为 32.3±2.8 周(均数±标准差)和 33.2 周(中位数),分别有 97%、61%和 14%的妇女在小于 37 周、小于 34 周和小于 30 周分娩。对于活产儿,最重、中间和最轻三胞胎的平均出生体重分别为 1762±437 g、1608±396 g 和 1406±380 g。18 名(5.6%)妇女发生围产儿死亡(1 名妇女 3 例,4 名妇女 2 例,13 名妇女 1 例)。围产儿死亡率为每 1000 例分娩 25 例死亡,且随绒毛膜膜数目的增加而降低(每 1000 例单绒毛膜、双绒毛膜和三绒毛膜三胞胎分娩的死亡率分别为 125、44 和 20)。

结论

日本三胞胎妊娠的短期结局良好。这些数据可能对有三胞胎妊娠的日本妇女的咨询有用。

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