Department of Pathology, Xuzhou Medical College, Xuzhou, 221002, China.
Hum Pathol. 2013 Apr;44(4):664-9. doi: 10.1016/j.humpath.2012.09.011. Epub 2013 Jan 11.
Peripheral lymphadenopathy is a rare presentation in malignant mesothelioma. We describe a unique case of malignant mesothelioma arising in an 11-year-old boy, for whom peripheral lymphadenopathy was the initial manifestation of the disease. The final diagnosis was confirmed by a broad panel of immunohistochemical markers. Literature review disclosed only 2 cases in childhood that initially presented with peripheral lymphadenopathy. Pathologists should be aware of this rare biologic behavior of malignant mesothelioma to reach the correct and prompt diagnosis.
外周淋巴结病是恶性间皮瘤的罕见表现。我们描述了一例独特的发生在 11 岁男孩的恶性间皮瘤病例，该患者外周淋巴结病是疾病的初始表现。最终诊断通过广泛的免疫组化标志物得到确认。文献回顾仅发现 2 例儿童期初诊表现为外周淋巴结病的病例。病理学家应该意识到恶性间皮瘤这种罕见的生物学行为，以便做出正确和及时的诊断。
