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1
Rocky mountain spotted fever in the United States, 2000-2007: interpreting contemporary increases in incidence.美国 2000-2007 年落基山斑点热:解读发病率的当代增长。
Am J Trop Med Hyg. 2010 Jul;83(1):174-82. doi: 10.4269/ajtmh.2010.09-0752.
2
Rickettsiae and rickettsial infections: the current state of knowledge.立克次氏体及立克次氏体感染:当前的知识状况
Clin Infect Dis. 2007 Jul 15;45 Suppl 1:S39-44. doi: 10.1086/518145.
3
Rocky Mountain spotted fever.落基山斑疹热
J Eur Acad Dermatol Venereol. 2006 Apr;20(4):411-7. doi: 10.1111/j.1468-3083.2006.01489.x.
4
Rocky Mountain spotted fever from an unexpected tick vector in Arizona.来自亚利桑那州一种意外蜱虫媒介的落基山斑疹热。
N Engl J Med. 2005 Aug 11;353(6):587-94. doi: 10.1056/NEJMoa050043.
5
Rocky Mountain spotted fever: a clinician's dilemma.落基山斑疹热:临床医生的困境
Arch Intern Med. 2003 Apr 14;163(7):769-74. doi: 10.1001/archinte.163.7.769.
6
Rickettsial, ehrlichial and Bartonella infections of the myocardium and pericardium.
Front Biosci. 2003 Jan 1;8:e197-201. doi: 10.2741/995.
7
Rocky mountain spotted fever.落基山斑疹热
Med Clin North Am. 2002 Mar;86(2):351-60, vii-viii. doi: 10.1016/s0025-7125(03)00091-9.
8
Immunization with a portion of rickettsial outer membrane protein A stimulates protective immunity against spotted fever rickettsiosis.用立克次氏体外膜蛋白A的一部分进行免疫接种可刺激针对斑点热立克次体病的保护性免疫。
Vaccine. 2001 Dec 12;20(5-6):979-88. doi: 10.1016/s0264-410x(01)00377-2.
9
Analysis of risk factors for fatal Rocky Mountain Spotted Fever: evidence for superiority of tetracyclines for therapy.落基山斑疹热致死的危险因素分析:四环素治疗优势的证据
J Infect Dis. 2001 Dec 1;184(11):1437-44. doi: 10.1086/324372. Epub 2001 Nov 13.
10
Consequences of delayed diagnosis of Rocky Mountain spotted fever in children--West Virginia, Michigan, Tennessee, and Oklahoma, May--July 2000.2000年5月至7月西弗吉尼亚州、密歇根州、田纳西州和俄克拉何马州儿童落基山斑疹热延迟诊断的后果
Ann Emerg Med. 2001 May;37(5):537-40. doi: 10.1067/mem.2001.114907.

搭便车引发的问题:心肌炎、感染性休克及成人呼吸窘迫综合征的罕见病因

Hitch-hiker taken for a ride: an unusual cause of myocarditis, septic shock and adult respiratory distress syndrome.

作者信息

Kushawaha Anurag, Brown Mark, Martin Ismael, Evenhuis Walther

机构信息

Division of Hospital Medicine, Department of Internal Medicine, Naples Community Hospital, Florida, USA.

出版信息

BMJ Case Rep. 2013 Jan 11;2013:bcr2012007155. doi: 10.1136/bcr-2012-007155.

DOI:10.1136/bcr-2012-007155
PMID:23314875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3603717/
Abstract

Rocky Mountain spotted fever (RMSF) is a serious tick-borne illness caused by Rickettsia rickettsii that is endemic in southeastern USA. Although RMSF has been described as causing the classic clinical triad of fever, headache and a characteristic rash, serious and potentially life-threatening manifestations can occur. Cardiopulmonary involvement, although infrequent, may occur with severe cases of RMSF. Rickettsial myocarditis is an uncommon occurrence. We present a case of a previously healthy 26-year-old man, who was hitch-hiking across the southeastern USA, with serologically proven RMSF causing adult respiratory distress syndrome, septic shock and myocarditis manifested by elevated cardiac enzymes and decrease in myocardial function. After treatment with antibiotics, the myocarditis resolved. Therefore, although unusual, clinicians should be aware of possible myocardial involvement in patients with appropriate tick-exposure histories or other clinical signs of RMSF.

摘要

落基山斑疹热(RMSF)是一种由立氏立克次体引起的严重蜱传疾病,在美国东南部地区流行。尽管RMSF被描述为会引发发热、头痛和特征性皮疹这一典型临床三联征,但也可能出现严重且潜在危及生命的表现。心肺受累情况虽不常见,但在重症RMSF病例中可能发生。立克次体心肌炎并不常见。我们报告一例病例,一名既往健康的26岁男性,在美国东南部搭便车旅行,血清学证实患有RMSF,导致成人呼吸窘迫综合征、感染性休克和心肌炎,表现为心肌酶升高和心肌功能下降。经抗生素治疗后,心肌炎得以缓解。因此,尽管不常见,但临床医生应意识到,对于有适当蜱虫暴露史或其他RMSF临床体征的患者,可能存在心肌受累情况。