Jourabchi Natanel, Sauk Steven, Hoffman Cheryl, Lee Edward Wolfgang, Kee Stephen Thomas
Department of Radiology, David Geffen School of Medicine, UCLA Health System, Los Angeles, CA 90095, USA.
Case Rep Radiol. 2012;2012:146540. doi: 10.1155/2012/146540. Epub 2012 Dec 17.
Over the past decade, irinotecan has become one of the first-line chemotherapeutic agents used in the treatment of metastatic colorectal cancer. Recently, irinotecan has been administered transarterially in order to perform chemoembolization in the liver. In the limited number of reports available to date using this approach, serious adverse effects have not yet been reported. In this paper, we describe the formation of an intercostal artery pseudoaneurysm after transarterial chemoembolization with irinotecan-eluting beads in a patient with spinal metastasis from colorectal cancer.
在过去十年中,伊立替康已成为治疗转移性结直肠癌的一线化疗药物之一。最近,伊立替康已通过动脉内给药以在肝脏中进行化疗栓塞。在迄今为止使用这种方法的有限数量的报告中,尚未报告严重的不良反应。在本文中,我们描述了一名患有结直肠癌脊柱转移的患者在使用载有伊立替康的微球进行动脉内化疗栓塞后出现肋间动脉假性动脉瘤的情况。