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有限减压联合椎板重建在单节段胸椎结核治疗中的应用

[Application of limited decompression combined with vertebral plate reconstruction on treatment of single segment thoracic vertebra tuberculosis].

作者信息

Luo Yi, Deng Zhansheng, Chen Jing, Guo Chaofeng

机构信息

Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha Hunan, 410008, P.R. China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2012 Dec;26(12):1409-14.

Abstract

OBJECTIVE

To investigate the effectiveness in the treatment of single segment thoracic vertebra tuberculosis by limited decompression combined with epidural absorbable haemostat covering and vertebral plate reconstruction based on one-stage posterior approach, debridement, bone fusion, and internal fixation.

METHODS

Between September 2005 and March 2010, 90 cases of single segment thoracic vertebra tuberculosis were treated by using limited decompression combined with epidural absorbable haemostat covering and vertebral plate reconstruction based on one-stage posterior approach, debridement, bone fusion, and internal fixation in 44 patients (treatment group) and by one-stage posterior approach, bone fusion, and internal fixation in 46 patients (control group). There was no significant difference in gender, age, disease duration, affected segment, Cobb angle, Frankle grade, erythrocyte sedimentation rate (ESR), and Oswestry disability index (ODI) between 2 groups (P > 0.05).

RESULTS

All incisions healed by first intension. All 90 cases were followed up 24-44 months (mean, 38 months). There was no significant difference in ESR between 2 groups at 1 week and 3 months after operation (P > 0.05). Postoperative iconography indicated that the bone fusion rate of the treatment group was 100% and no epidural cicatricial tissue or failure of internal fixation was observed, showing significant difference when compared with control group (3 cases having failure of internal fixation) (P = 0.032). The Cobb angles were significantly corrected after operation when compared with preoperative angles in 2 groups (P < 0.05). At 2 years after operation and at last follow-up, the Cobb angle and correction loss in treatment group were significantly better than those in control group (P < 0.05). The ODI and Frankel grade were significantly improved at last follow-up when compared with preoperative ones in 2 groups (P < 0.05); the treatment group was significantly better than the control group in the ODI, improvement rate of ODI (P < 0.05), and in Frankel grade (Uc = 4.368, P = 0.000).

CONCLUSION

Compared with conventional operation method, it is an ideal operation method to use limited decompression combined with epidural absorbable haemostat covering and vertebral plate reconstruction based on one-stage posterior approach, debridement, bone fusion, and internal fixation for treatment of single segment thoracic vertebra tuberculosis, with minimal wound, less complications, and good function recovery.

摘要

目的

探讨一期后路有限减压、病灶清除、植骨融合、内固定并联合应用硬膜外可吸收止血纱布覆盖及椎板重建治疗单节段胸椎结核的疗效。

方法

2005年9月至2010年3月,对90例单节段胸椎结核患者采用一期后路有限减压、病灶清除、植骨融合、内固定并联合应用硬膜外可吸收止血纱布覆盖及椎板重建治疗44例(治疗组),采用一期后路病灶清除、植骨融合、内固定治疗46例(对照组)。两组患者性别、年龄、病程、病变节段、Cobb角、Frankle分级、血沉(ESR)及Oswestry功能障碍指数(ODI)比较差异无统计学意义(P > 0.05)。

结果

所有切口均一期愈合。90例患者均获随访,随访时间24~44个月,平均38个月。术后1周及3个月时两组ESR比较差异无统计学意义(P > 0.05)。术后影像学检查显示治疗组植骨融合率为100%,未观察到硬膜外瘢痕组织及内固定失败,与对照组(3例内固定失败)比较差异有统计学意义(P = 0.032)。两组术后Cobb角较术前均明显矫正(P < 0.05)。术后2年及末次随访时,治疗组Cobb角及矫正丢失情况均明显优于对照组(P < 0.05)。两组末次随访时ODI及Frankle分级较术前均明显改善(P < 0.05);治疗组ODI、ODI改善率明显优于对照组(P < 0.05),Frankle分级也明显优于对照组(Uc = 4.368,P = 0.000)。

结论

与传统手术方法相比,一期后路有限减压、病灶清除、植骨融合、内固定并联合应用硬膜外可吸收止血纱布覆盖及椎板重建治疗单节段胸椎结核,创伤小、并发症少、功能恢复好,是一种理想的手术方法。

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