Goldberg Ilan
Dermatology Department, Tel-Aviv Sourasky Medical Center.
Harefuah. 2012 Oct;151(10):581-4, 604.
Mycosis fungoides (MF) is the most prevalent cutaneous lymphoma, characterized by uncontrolled growth of T cells within the skin. The diagnosis in the early stages may be difficult, since, in these stages, the disease can imitate benign inflammatory processes, both clinically and histologically. One of the difficulties in determining diagnostic criteria for early MF is the existing terminology of parapsoriasis. There is disagreement concerning the exact definition and whether it is a chronic benign condition with similar clinical and histological characteristics as MF, or rather it is part of the disease spectrum itself. There is a need for uniformity in the definition for treatment decisions, for epidemiological purposes and for clinical and experimental research. This article reviews the different approaches to parapsoriasis as part of MF over the years.
蕈样肉芽肿(MF)是最常见的皮肤淋巴瘤,其特征是皮肤内T细胞不受控制地生长。早期诊断可能较为困难,因为在这些阶段,该疾病在临床和组织学上都可能模仿良性炎症过程。确定早期MF诊断标准的困难之一在于副银屑病的现有术语。关于其确切定义以及它是一种具有与MF相似临床和组织学特征的慢性良性疾病,还是本身就是疾病谱的一部分,存在分歧。为了治疗决策、流行病学目的以及临床和实验研究,需要在定义上保持统一。本文回顾了多年来将副银屑病视为MF一部分的不同方法。