Rokitansky A, Wolner E
II. chirurgická univerzitní klinika, Víden, Allgemeines Krankenhaus, Wien.
Cas Lek Cesk. 1990 Mar 2;129(9):257-62.
Acute, uncontrollable heart failure in young candidates for transplantation should be considered an indication for implantation of an artificial heart or artificial support of the hear ventricle, if a suitable graft for transplantation is not available at the time. It may be assumed that the two systems will ensure an adequate circulation and will improve organ function. The success of two-stage transplantation is cca 50%. Postoperative haemorrhage and infection are a major problem. Infection after implantation of an artificial heart is frequently incurable and is a clear contra-indication for further implantation. Thromboembolism caused by the artificial blood pump does not seem to be a serious complication when used temporarily. As none of the patients died due to failure of the pump and as also the other problems associated with the use of an artificial heart or a supporting device were successfully resolved, research and development of artificial blood pumps should proceed. Clinical results also confirmed the success of two-stage transplantation of the heart.
对于年轻的心脏移植候选者,如果当时没有合适的移植供体,急性、无法控制的心力衰竭应被视为植入人工心脏或心室人工支持装置的指征。可以假定这两种系统将确保足够的循环并改善器官功能。两阶段移植的成功率约为50%。术后出血和感染是一个主要问题。植入人工心脏后的感染通常无法治愈,是进一步植入的明确禁忌证。人工血泵引起的血栓栓塞在临时使用时似乎不是严重并发症。由于没有患者因泵功能衰竭死亡,并且与使用人工心脏或支持装置相关的其他问题也得到了成功解决,人工血泵的研发应该继续进行。临床结果也证实了心脏两阶段移植的成功。