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[强直性肌营养不良症骨骼肌的计算机断层扫描]

[Computed tomography of skeletal muscles in myotonic muscular dystrophy].

作者信息

Miyashita I, Yamamoto H, Koga H, Kani K, Mori K

机构信息

Department of Neurology, Fujita-Gakuen Health University School of Medicine.

出版信息

Rinsho Shinkeigaku. 1990 Jan;30(1):24-8.

PMID:2331819
Abstract

The computed tomography (CT) of skeletal muscles was performed on 12 patients with myotonic muscular dystrophy (MyD). We have sliced at seven levels; those are 1. neck level-at the level of thyroid cartilage 2. shoulder girdle level-at the level of upper edge of sternum 3. upper arm level-at the level of middle of upper arm 4. abdominal level-at the level of L3 vertebra 5. pelvic girdle level-at the level of middle inguinal ligament 6. thigh level-at the level of middle of thigh 7. lower leg level-at the maximum size level of lower leg. The characteristic changes of MyD are; the sternocleidomastoid muscles are most severely affected, and the paravertebral and straight abdominal muscles also tend to be severely atrophied with lower CT density. Concerning thigh levels, the deeply located muscles and muscles for extension are predominantly affected. At the lower leg levels, the calf muscles are severely affected. The muscles of levator scapulae, trapezius, psoas major, iliopsoas, gluteus, and tibialis posterior tend to be preserved. In the tight, the compensatory hypertrophy is observed often in the rectus femoris muscles and rarely in the gracilis muscles with the involvements of the agonist muscles. It might be also important to examine the changes of muscles as a whole and to know the grade of atrophy for planning the life style. The CT examination would be recommended by this standpoint.

摘要

对12例强直性肌营养不良(MyD)患者进行了骨骼肌的计算机断层扫描(CT)检查。我们在7个层面进行了切片,分别是:1. 颈部层面——甲状软骨水平;2. 肩胛带层面——胸骨上缘水平;3. 上臂层面——上臂中部水平;4. 腹部层面——L3椎体水平;5. 骨盆带层面——腹股沟韧带中部水平;6. 大腿层面——大腿中部水平;7. 小腿层面——小腿最大径层面。MyD的特征性改变为:胸锁乳突肌受影响最严重,椎旁肌和腹直肌也往往严重萎缩,CT密度降低。在大腿层面,深部肌肉和伸展肌受影响为主。在小腿层面,小腿肌肉受影响严重。肩胛提肌、斜方肌、腰大肌、髂腰肌、臀肌和胫后肌往往得以保留。在病情严重时,股直肌常出现代偿性肥大,而在拮抗肌受累时,股薄肌很少出现代偿性肥大。从整体上检查肌肉变化并了解萎缩程度对于规划生活方式可能也很重要。从这个角度来看,建议进行CT检查。

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