Service d'hépato-gastroentérologie, CHU de Limoges, 2, avenue Martin-Luther-King, 87042 Limoges, France.
Clin Res Hepatol Gastroenterol. 2013 Feb;37(1):100-4. doi: 10.1016/j.clinre.2012.10.015. Epub 2013 Jan 11.
The occurrence of corticosteroid-induced hepatitis is a rare event that has been recently described in the literature. We report the case of an acute cytolytic hepatitis in a patient treated with methylprednisolone for multiple sclerosis associated with an autoimmune thyroid dysfunction. After ruling out other etiologies, we concluded that the acute liver injury was due to steroids, and we analyzed the specific circumstances in the literature where methylprednisolone may have been responsible for acute hepatitis.
皮质类固醇诱导性肝炎的发生是一种罕见事件，最近在文献中有所描述。我们报告了一例多发性硬化症患者在接受甲基强的松龙治疗时发生的急性细胞溶解性肝炎，并伴有自身免疫性甲状腺功能障碍。在排除其他病因后，我们得出结论，急性肝损伤是由类固醇引起的，并分析了文献中甲基强的松龙可能导致急性肝炎的具体情况。
