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EGFR-STAT3 signaling promotes formation of malignant peripheral nerve sheath tumors.
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Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis.
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Inhibition of the JAK2/STAT3 signaling pathway exerts a therapeutic effect on osteosarcoma.
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Brain lipid binding protein in axon-Schwann cell interactions and peripheral nerve tumorigenesis.
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Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK.
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Emerging mechanism and therapeutic potential of neurofibromatosis type 1-related nerve system tumor: Advancing insights into tumor development.
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PET Imaging of Neurofibromatosis Type 1 with a Fluorine-18 Labeled Tryptophan Radiotracer.
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Curcumin and its Analogues in Oral Squamous Cell Carcinoma: State-of-the-art and Therapeutic Potential.
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Comprehensive pan-cancer analysis of STAT3 as a prognostic and immunological biomarker.
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Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury.
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2
Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors.
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Activated MET is a molecular prognosticator and potential therapeutic target for malignant peripheral nerve sheath tumors.
Clin Cancer Res. 2011 Jun 15;17(12):3943-55. doi: 10.1158/1078-0432.CCR-11-0193. Epub 2011 May 3.
7
Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.
Cancer Cell. 2011 Apr 12;19(4):441-55. doi: 10.1016/j.ccr.2011.03.002.
8
Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells.
Cancer Res. 2010 Mar 15;70(6):2445-54. doi: 10.1158/0008-5472.CAN-09-2468. Epub 2010 Mar 9.

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