Department of Internal Medicine, Texas Health Presbyterian Hospital Dallas and University of Texas Southwestern Medical School, Dallas, Texas 75231, USA.
Am J Gastroenterol. 2013 Mar;108(3):347-52. doi: 10.1038/ajg.2012.478. Epub 2013 Jan 15.
Serious, life-threatening conditions may result from too much gastric acid secretion by parietal cells, too little secretion of gastric acid and intrinsic factor by parietal cells, or loss of secreted gastric hydrochloric acid from the body. Understanding the physiology and pathophysiology of gastric secretion and its regulation can improve patient care and clinical outcomes. Gastric secretion remains highly relevant to practicing clinicians.
壁细胞分泌过多胃酸、壁细胞分泌胃酸和内在因子过少、以及分泌的胃酸从体内流失,这些情况都可能导致严重的、危及生命的状况。了解胃酸分泌的生理学和病理生理学及其调节机制可以改善患者的护理和临床结果。胃酸分泌仍然与临床医生的实践密切相关。