State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.
Appl Microbiol Biotechnol. 2013 Mar;97(5):1821-7. doi: 10.1007/s00253-013-4687-2. Epub 2013 Jan 15.
Epilactose (4-O-β-D-galactopyranosyl-D-mannose), an epimer of lactose, is a rare disaccharide existing extremely small quantities in heat-treated milk, in which epilactose is produced by non-enzymatic catalysis from lactose. This disaccharide is a kind of non-digestible carbohydrate, has a good prebiotic effect, and promotes intestinal mineral absorption. This article presents a review of recent studies on epilactose formation in food system, qualitative and quantitative analysis, and its physiological functions. In addition, the biochemical properties and kinetic parameters of the epilactose-producing enzyme, cellobiose 2-epimerase, are compared, and the biotechnological production of epilactose from lactose is reviewed.
低聚半乳糖（4-O-β-D-半乳糖吡喃糖苷-D-甘露糖）是乳糖的差向异构体，是一种罕见的二糖，在热处理的牛奶中含量极微，其中，低聚半乳糖是由乳糖在非酶催化作用下产生的。这种二糖是一种不可消化的碳水化合物，具有良好的益生元作用，并促进肠道矿物质吸收。本文综述了食品体系中低聚半乳糖形成的最新研究、定性和定量分析及其生理功能。此外，还比较了产低聚半乳糖酶（纤维二糖 2-差向异构酶）的生化特性和动力学参数，并综述了从乳糖生物合成低聚半乳糖的技术。
