Hartmann S, Hansmann M L
Senckenbergisches Institut für Pathologie, Klinikum der J. W. Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.
Pathologe. 2013 Feb;34(1):34-44. doi: 10.1007/s00292-012-1706-5.
Immune suppression is a risk factor for malignant lymphoma development. Progress in medical science has increased the numbers of immunosuppressed patients due to organ transplantations or successful treatment of autoimmune diseases. Different forms of immune suppression and the respective lymphoma entities are discussed in this article. Another issue treated are gray zone lymphomas between Hodgkin's lymphoma and diffuse large B cell lymphoma. This category not only represents a diagnostic challenge but also represents more a true biological continuum.
免疫抑制是恶性淋巴瘤发生的一个危险因素。医学的进步使得因器官移植或自身免疫性疾病的成功治疗而导致的免疫抑制患者数量增加。本文讨论了不同形式的免疫抑制以及相应的淋巴瘤实体。另一个探讨的问题是霍奇金淋巴瘤和弥漫性大B细胞淋巴瘤之间的灰色地带淋巴瘤。这一类别不仅代表了诊断上的挑战,而且更代表了一种真正的生物学连续体。