Matlach J, Göbel W
Augenklinik und Poliklinik, Universitätsklinikum Würzburg, Josef-Schneider-Str. 11, 97080, Würzburg, Deutschland.
Ophthalmologe. 2013 Feb;110(2):169-72. doi: 10.1007/s00347-012-2764-z.
Behçet's disease is a chronic recurrent systemic vasculitis and can affect nearly all organ systems. Eye involvement is characterized by uveitis with occlusive retinal vasculitis. Oral aphthous ulcers are the major primary symptom and arthritis, genital ulcerations and skin lesions are common extraocular manifestations. Gastrointestinal and vascular symptoms or manifestations of the central nervous system are less frequently seen. Biologic agents are used alone or in combination with immunosuppressive or cytotoxic drugs to prevent relapse as the prognosis is poor in patients with retinal vasculitis.
白塞病是一种慢性复发性系统性血管炎，几乎可累及所有器官系统。眼部受累的特征为葡萄膜炎伴闭塞性视网膜血管炎。口腔阿弗他溃疡是主要的首发症状，关节炎、生殖器溃疡和皮肤病变是常见的眼外表现。胃肠道和血管症状或中枢神经系统表现则较少见。由于视网膜血管炎患者的预后较差，生物制剂单独使用或与免疫抑制或细胞毒性药物联合使用以预防复发。
