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P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control.
Int J Physiol Pathophysiol Pharmacol. 2012;4(4):174-87. Epub 2012 Dec 26.
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P2X receptors as targets for the treatment of status epilepticus.
Front Cell Neurosci. 2013 Nov 26;7:237. doi: 10.3389/fncel.2013.00237.
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P2X7 receptor inhibition interrupts the progression of seizures in immature rats and reduces hippocampal damage.
CNS Neurosci Ther. 2014 Jun;20(6):556-64. doi: 10.1111/cns.12272. Epub 2014 Apr 21.
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P2X purinoceptors as a link between hyperexcitability and neuroinflammation in status epilepticus.
Epilepsy Behav. 2015 Aug;49:8-12. doi: 10.1016/j.yebeh.2015.02.031. Epub 2015 Apr 3.

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The Multifaceted Role of P2X7R in Microglia and Astrocytes.
Neurochem Res. 2025 Jul 21;50(4):239. doi: 10.1007/s11064-025-04502-y.
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Purinergic Receptor (P2X7R): A Promising Anti-Parkinson's Drug Target.
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Pannexin1 Mediates Early-Life Seizure-Induced Social Behavior Deficits.
ASN Neuro. 2024;16(1):2371164. doi: 10.1080/17590914.2024.2371164. Epub 2024 Jul 16.
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Neuroinflammation and status epilepticus: a narrative review unraveling a complex interplay.
Front Pediatr. 2023 Nov 21;11:1251914. doi: 10.3389/fped.2023.1251914. eCollection 2023.
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Analyzing the Role of the P2X7 Receptor in Epilepsy.
Methods Mol Biol. 2022;2510:367-387. doi: 10.1007/978-1-0716-2384-8_21.
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Antagonistic Roles of P2X7 and P2Y2 Receptors in Neurodegenerative Diseases.
Front Pharmacol. 2021 Apr 12;12:659097. doi: 10.3389/fphar.2021.659097. eCollection 2021.

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2
Pharmacoresistance and the role of surgery in difficult to treat epilepsy.
Nat Rev Neurol. 2012 Dec;8(12):669-77. doi: 10.1038/nrneurol.2012.181. Epub 2012 Sep 11.
3
Activation of P2X7 promotes cerebral edema and neurological injury after traumatic brain injury in mice.
PLoS One. 2012;7(7):e41229. doi: 10.1371/journal.pone.0041229. Epub 2012 Jul 17.
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5
P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia.
Neurobiol Dis. 2012 Mar;45(3):954-61. doi: 10.1016/j.nbd.2011.12.014. Epub 2011 Dec 11.
6
Experimental models of seizures and epilepsies.
Prog Mol Biol Transl Sci. 2012;105:57-82. doi: 10.1016/B978-0-12-394596-9.00003-2.
7
In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases.
Neurobiol Aging. 2012 Aug;33(8):1816-28. doi: 10.1016/j.neurobiolaging.2011.09.040. Epub 2011 Nov 1.
8
Targeting pannexin1 improves seizure outcome.
PLoS One. 2011;6(9):e25178. doi: 10.1371/journal.pone.0025178. Epub 2011 Sep 16.
9
The roles of P2X7 receptor in regional-specific microglial responses in the rat brain following status epilepticus.
Neurol Sci. 2012 Jun;33(3):515-25. doi: 10.1007/s10072-011-0740-z. Epub 2011 Aug 16.

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