Abbas Ozan Luay, Borman Huseyin
Department of Plastic, Reconstructive and Aesthetic Surgery, Baskent University Faculty of Medicine, 40000 Ankara, Turkey.
ISRN Dermatol. 2012;2012:246542. doi: 10.5402/2012/246542. Epub 2012 Dec 22.
Background. Basal cell carcinoma comprises the vast majority of skin cancers. It predominantly affects fair-skinned individuals, and its incidence is rising rapidly. Etiology may be multifactorial, but sun exposure appears to play a critical role. When detected early, the prognosis is excellent. Thus appropriate diagnosis, treatment, and surveillance are of utmost importance. Methods. From January 1994 to May 2012, 518 basal cell carcinomas were excised in our clinic. Data were collected retrospectively. Results. During 18-year period, 518 BCCs were excised from 486 patients. Most of the patients were males with a median age of 65.6 years. Most of the basal cell carcinomas were located in the head region. Nodular histological subtype dominated our series. Six percent of the excised lesions required reexcision because of involved margins. Our recurrence rate was 6.94% with the nose and the periauricular and periocular regions being the most common sites of occurrence. Conclusion. Although there is relatively low attributable mortality, the morbidity and cost of treatment are significant. A large body of information serves as a foundation for oncologic principles, diagnosis methods, surgical excisions, follow-up protocols, and reconstructive methodologies that are currently in use. Surgical ablation remains the mainstay of treatment.
背景。基底细胞癌占皮肤癌的绝大多数。它主要影响皮肤白皙的个体，且其发病率正在迅速上升。病因可能是多因素的，但阳光照射似乎起着关键作用。早期发现时，预后良好。因此，恰当的诊断、治疗和监测至关重要。方法。1994年1月至2012年5月，我们诊所切除了518例基底细胞癌。数据进行回顾性收集。结果。在18年期间，从486例患者身上切除了518例基底细胞癌。大多数患者为男性，中位年龄为65.6岁。大多数基底细胞癌位于头部区域。结节状组织学亚型在我们的病例系列中占主导。6%的切除病变因切缘受累需要再次切除。我们的复发率为6.94%，鼻子、耳周和眼周区域是最常见的复发部位。结论。尽管归因死亡率相对较低，但治疗的发病率和成本很高。大量信息为目前使用的肿瘤学原则、诊断方法、手术切除、随访方案和重建方法奠定了基础。手术切除仍然是主要的治疗方法。
