Smith T J, Hautamaa D, Maeda N
Department of Pathology, University of North Carolina, Chapel Hill 27599-7525.
Gene. 1990 Mar 15;87(2):309-10. doi: 10.1016/0378-1119(90)90319-m.
The nucleotide sequences of 2.35 kb of the apoB genes (encoding apolipoprotein B) encompassing the low-density-lipoprotein receptor-binding domains from mouse and hamster, have been determined. The sequences are 87.6% identical at the DNA level and 84.6% identical at the protein level. The region is also highly conserved in pig and human.
已测定了小鼠和仓鼠载脂蛋白B基因 2.35 kb 的核苷酸序列(编码载脂蛋白B),该序列包含低密度脂蛋白受体结合结构域。在DNA水平上,这些序列的相似度为87.6%,在蛋白质水平上为84.6%。该区域在猪和人类中也高度保守。