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[局部免疫调节在治疗HIV感染患者疱疹性感染中的应用]

[Topical immunomodulation in the treatment of herpetic infections in HIV-infected patients].

作者信息

Shul'diakov A A, Barkhatova T S, Zubareva E V, Satarova S A, Perminova T A

出版信息

Eksp Klin Farmakol. 2012;75(11):35-7.

PMID:23323332
Abstract

The efficiency of cycloferon liniment in combined treatment of herpetic infection in patients with latent form of HIV infection has been assess by observations of 40 patients divided into two groups. In the first group, the standard treatment was supplemented with the application of cycloferon liniment twice a day during 7 days; in the second group, the therapy was conducted according to standard recommendations. It was established that the application of cycloferon liniment in combination with standard therapy in patients with relapse of herpetic infection against the background of HIV infection ensures faster disappearance of general infectious syndrome, decreases the period of eruptions and the duration of local inflammations, and accelerates the epithelialization of erosions.

摘要

通过对40例患者的观察评估了环孢素搽剂在合并潜伏性HIV感染患者疱疹感染联合治疗中的疗效,这些患者被分为两组。第一组在标准治疗的基础上,每天两次外用环孢素搽剂,共7天;第二组按照标准推荐进行治疗。结果表明,在HIV感染背景下疱疹感染复发的患者中,环孢素搽剂与标准治疗联合应用可确保全身感染综合征更快消失,缩短皮疹期和局部炎症持续时间,并加速糜烂面的上皮化。

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